Risk factors for periprosthetic joint infection after total hip arthroplasty and total knee arthroplasty in Chinese patients.
PURPOSE: The purpose of this hospital-based case-control study was to evaluate the risk factors for periprosthetic joint infection (PJI) of total hip arthroplasty (THA) and total knee arthroplasty (TKA) in Chinese patients. METHOD: From January 2000 to December 2012, 45 patients undergoing THA and T...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2014-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC3991645?pdf=render |
| _version_ | 1811274099892158464 |
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| author | Chuanlong Wu Xinhua Qu Fengxiang Liu Huiwu Li Yuanqing Mao Zhenan Zhu |
| author_facet | Chuanlong Wu Xinhua Qu Fengxiang Liu Huiwu Li Yuanqing Mao Zhenan Zhu |
| author_sort | Chuanlong Wu |
| collection | DOAJ |
| description | PURPOSE: The purpose of this hospital-based case-control study was to evaluate the risk factors for periprosthetic joint infection (PJI) of total hip arthroplasty (THA) and total knee arthroplasty (TKA) in Chinese patients. METHOD: From January 2000 to December 2012, 45 patients undergoing THA and TKA who developed PJI were recruited for case subjects; controls were 252 without PJI, matched by year of index for surgery and type of surgery. Conditional logistic regressions were run to compute odds ratios (ORs) and 95% confidence intervals (CIs). RESULTS: Demographic factors and comorbid conditions associated with an increased adjusted risk of PJI (in decreasing order of significance) were diabetes (OR = 5.47, 95% CI: 1.77-16.97; p = 0.003), age (65-75 vs. 45-65 years) (OR = 3.36, 95% CI: 1.30-8.69; p = 0.013), BMI (≥28 vs. 18.5-28 kg/m2) (OR = 2.77, 95% CI: 1.20-6.40; p = 0.017), place of residence (rural) (OR = 2.63, 95% CI: 1.13-6.10; p = 0.025) and alcohol abuse (OR = 2.95, 95% CI: 1.06-8.23; p = 0.039). CONCLUSION: Patients with diabetes, older age, BMI of ≥28 kg/m2 and alcohol abuse or living in rural areas, had increased PJI risk. Additional systematic large-scale studies are needed to verify these results. |
| first_indexed | 2024-04-12T23:12:56Z |
| format | Article |
| id | doaj.art-a3545892ab2e40058a51122b9d04b400 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-04-12T23:12:56Z |
| publishDate | 2014-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-a3545892ab2e40058a51122b9d04b4002022-12-22T03:12:46ZengPublic Library of Science (PLoS)PLoS ONE1932-62032014-01-0194e9530010.1371/journal.pone.0095300Risk factors for periprosthetic joint infection after total hip arthroplasty and total knee arthroplasty in Chinese patients.Chuanlong WuXinhua QuFengxiang LiuHuiwu LiYuanqing MaoZhenan ZhuPURPOSE: The purpose of this hospital-based case-control study was to evaluate the risk factors for periprosthetic joint infection (PJI) of total hip arthroplasty (THA) and total knee arthroplasty (TKA) in Chinese patients. METHOD: From January 2000 to December 2012, 45 patients undergoing THA and TKA who developed PJI were recruited for case subjects; controls were 252 without PJI, matched by year of index for surgery and type of surgery. Conditional logistic regressions were run to compute odds ratios (ORs) and 95% confidence intervals (CIs). RESULTS: Demographic factors and comorbid conditions associated with an increased adjusted risk of PJI (in decreasing order of significance) were diabetes (OR = 5.47, 95% CI: 1.77-16.97; p = 0.003), age (65-75 vs. 45-65 years) (OR = 3.36, 95% CI: 1.30-8.69; p = 0.013), BMI (≥28 vs. 18.5-28 kg/m2) (OR = 2.77, 95% CI: 1.20-6.40; p = 0.017), place of residence (rural) (OR = 2.63, 95% CI: 1.13-6.10; p = 0.025) and alcohol abuse (OR = 2.95, 95% CI: 1.06-8.23; p = 0.039). CONCLUSION: Patients with diabetes, older age, BMI of ≥28 kg/m2 and alcohol abuse or living in rural areas, had increased PJI risk. Additional systematic large-scale studies are needed to verify these results.http://europepmc.org/articles/PMC3991645?pdf=render |
| spellingShingle | Chuanlong Wu Xinhua Qu Fengxiang Liu Huiwu Li Yuanqing Mao Zhenan Zhu Risk factors for periprosthetic joint infection after total hip arthroplasty and total knee arthroplasty in Chinese patients. PLoS ONE |
| title | Risk factors for periprosthetic joint infection after total hip arthroplasty and total knee arthroplasty in Chinese patients. |
| title_full | Risk factors for periprosthetic joint infection after total hip arthroplasty and total knee arthroplasty in Chinese patients. |
| title_fullStr | Risk factors for periprosthetic joint infection after total hip arthroplasty and total knee arthroplasty in Chinese patients. |
| title_full_unstemmed | Risk factors for periprosthetic joint infection after total hip arthroplasty and total knee arthroplasty in Chinese patients. |
| title_short | Risk factors for periprosthetic joint infection after total hip arthroplasty and total knee arthroplasty in Chinese patients. |
| title_sort | risk factors for periprosthetic joint infection after total hip arthroplasty and total knee arthroplasty in chinese patients |
| url | http://europepmc.org/articles/PMC3991645?pdf=render |
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