Focal Adhesion Kinase (FAK)-Hippo/YAP transduction signaling mediates the stimulatory effects exerted by S100A8/A9-RAGE system in triple-negative breast cancer (TNBC)

Focal Adhesion Kinase (FAK)-Hippo/YAP transduction signaling mediates the stimulatory effects exerted by S100A8/A9-RAGE system in triple-negative breast cancer (TNBC)

Abstract Background Understanding the intricate signaling network involved in triple-negative breast cancer (TNBC) represents a challenge for developing novel therapeutic approaches. Here, we aim to provide novel mechanistic insights on the function of the S100A8/A9-RAGE system in TNBC. Methods TNM...

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Bibliographic Details
Main Authors: Damiano Cosimo Rigiracciolo, Nijiro Nohata, Rosamaria Lappano, Francesca Cirillo, Marianna Talia, Sendi Rafael Adame-Garcia, Nadia Arang, Simone Lubrano, Ernestina Marianna De Francesco, Antonino Belfiore, J. Silvio Gutkind, Marcello Maggiolini
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
TNBC
MDA-MB-231
BT-549
S100A8/A9
RAGE
FAK
Online Access:https://doi.org/10.1186/s13046-022-02396-0

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