Autophagy enhances mesenchymal stem cell-mediated CD4+ T cell migration and differentiation through CXCL8 and TGF-β1

Autophagy enhances mesenchymal stem cell-mediated CD4+ T cell migration and differentiation through CXCL8 and TGF-β1

Abstract Background Mesenchymal stem cells (MSCs) have been recognized as a promising tool for the treatment of various inflammatory disorders and autoimmune diseases. Stress conditions affect immune-mediated treatment and activate autophagy in MSCs. However, whether autophagy affects the MSC-mediat...

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Bibliographic Details
Main Authors: Shuizhong Cen, Peng Wang, Zhongyu Xie, Rui Yang, Jinteng Li, Zhenhua Liu, Shan Wang, Xiaohua Wu, Wenjie Liu, Ming Li, Su’an Tang, Huiyong Shen, Yanfeng Wu
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Stem Cell Research & Therapy
Subjects:
Autophagy
Mesenchymal stem cells
Immunomodulatory
Migration
CD4+ T cells
Online Access:http://link.springer.com/article/10.1186/s13287-019-1380-0

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