Numerical simulation of a microfluidic biosensor for C-reactive protein detection into a microchannel with considering electrothermal effect
The performance enhancement of an electrothermal effect-based biosensor is studied numerically in this research. Indeed, the study of a microfluidic biosensor is used to detect the C-reactive protein into a microchannel with considering electrothermal effect. In the presence of the electrical field,...
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Format: | Article |
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Elsevier
2020-06-01
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Series: | Alexandria Engineering Journal |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S1110016820301538 |
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author | Hassnia Hajji Lioua Kolsi Kaouther Ghachem Chemseddine Maatki Mohamed Naceur Borjini |
author_facet | Hassnia Hajji Lioua Kolsi Kaouther Ghachem Chemseddine Maatki Mohamed Naceur Borjini |
author_sort | Hassnia Hajji |
collection | DOAJ |
description | The performance enhancement of an electrothermal effect-based biosensor is studied numerically in this research. Indeed, the study of a microfluidic biosensor is used to detect the C-reactive protein into a microchannel with considering electrothermal effect. In the presence of the electrical field, the produced Joule effect gives rise to a temperature gradient and causes homogeneities of electric permittivity and conductivity allowing the generation of flow motions. To improve the rate of reactant ransport via an on-surface-reaction in the microchannel, various pairs of electrodes under Alternating current (AC) are used and the effects of different arrangements and positions on flow structure, temperature and concentration fields, were investigated. In addition, the comparison with earliest results shows a good agreement. |
first_indexed | 2024-12-21T17:52:08Z |
format | Article |
id | doaj.art-a358afc96012407992ba4c9fc8b630b4 |
institution | Directory Open Access Journal |
issn | 1110-0168 |
language | English |
last_indexed | 2024-12-21T17:52:08Z |
publishDate | 2020-06-01 |
publisher | Elsevier |
record_format | Article |
series | Alexandria Engineering Journal |
spelling | doaj.art-a358afc96012407992ba4c9fc8b630b42022-12-21T18:55:18ZengElsevierAlexandria Engineering Journal1110-01682020-06-0159316491659Numerical simulation of a microfluidic biosensor for C-reactive protein detection into a microchannel with considering electrothermal effectHassnia Hajji0Lioua Kolsi1Kaouther Ghachem2Chemseddine Maatki3Mohamed Naceur Borjini4Research Laboratory of Metrology and Energy Systems, LR18ES21, National Engineering School, University of Monastir, TunisiaDepartment of Mechanical Engineering, College of Engineering, Hai’l University, Hai’l City, Saudi Arabia; Corresponding authors.Department of Industrial Engineering and Systems, College of Engineering, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia; Research Laboratory of Metrology and Energy Systems, LR18ES21, National Engineering School, University of Monastir, Tunisia; Corresponding authors.Department of Mechanical Engineering, College of Engineering, Al Imam Mohammad Ibn Saud Islamic University, Riyadh, Saudi ArabiaResearch Laboratory of Metrology and Energy Systems, LR18ES21, National Engineering School, University of Monastir, TunisiaThe performance enhancement of an electrothermal effect-based biosensor is studied numerically in this research. Indeed, the study of a microfluidic biosensor is used to detect the C-reactive protein into a microchannel with considering electrothermal effect. In the presence of the electrical field, the produced Joule effect gives rise to a temperature gradient and causes homogeneities of electric permittivity and conductivity allowing the generation of flow motions. To improve the rate of reactant ransport via an on-surface-reaction in the microchannel, various pairs of electrodes under Alternating current (AC) are used and the effects of different arrangements and positions on flow structure, temperature and concentration fields, were investigated. In addition, the comparison with earliest results shows a good agreement.http://www.sciencedirect.com/science/article/pii/S1110016820301538MicrochannelNumerical studyBiosensorAC electrothermal |
spellingShingle | Hassnia Hajji Lioua Kolsi Kaouther Ghachem Chemseddine Maatki Mohamed Naceur Borjini Numerical simulation of a microfluidic biosensor for C-reactive protein detection into a microchannel with considering electrothermal effect Alexandria Engineering Journal Microchannel Numerical study Biosensor AC electrothermal |
title | Numerical simulation of a microfluidic biosensor for C-reactive protein detection into a microchannel with considering electrothermal effect |
title_full | Numerical simulation of a microfluidic biosensor for C-reactive protein detection into a microchannel with considering electrothermal effect |
title_fullStr | Numerical simulation of a microfluidic biosensor for C-reactive protein detection into a microchannel with considering electrothermal effect |
title_full_unstemmed | Numerical simulation of a microfluidic biosensor for C-reactive protein detection into a microchannel with considering electrothermal effect |
title_short | Numerical simulation of a microfluidic biosensor for C-reactive protein detection into a microchannel with considering electrothermal effect |
title_sort | numerical simulation of a microfluidic biosensor for c reactive protein detection into a microchannel with considering electrothermal effect |
topic | Microchannel Numerical study Biosensor AC electrothermal |
url | http://www.sciencedirect.com/science/article/pii/S1110016820301538 |
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