Numerical simulation of a microfluidic biosensor for C-reactive protein detection into a microchannel with considering electrothermal effect

The performance enhancement of an electrothermal effect-based biosensor is studied numerically in this research. Indeed, the study of a microfluidic biosensor is used to detect the C-reactive protein into a microchannel with considering electrothermal effect. In the presence of the electrical field,...

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Main Authors: Hassnia Hajji, Lioua Kolsi, Kaouther Ghachem, Chemseddine Maatki, Mohamed Naceur Borjini
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Alexandria Engineering Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1110016820301538
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author Hassnia Hajji
Lioua Kolsi
Kaouther Ghachem
Chemseddine Maatki
Mohamed Naceur Borjini
author_facet Hassnia Hajji
Lioua Kolsi
Kaouther Ghachem
Chemseddine Maatki
Mohamed Naceur Borjini
author_sort Hassnia Hajji
collection DOAJ
description The performance enhancement of an electrothermal effect-based biosensor is studied numerically in this research. Indeed, the study of a microfluidic biosensor is used to detect the C-reactive protein into a microchannel with considering electrothermal effect. In the presence of the electrical field, the produced Joule effect gives rise to a temperature gradient and causes homogeneities of electric permittivity and conductivity allowing the generation of flow motions. To improve the rate of reactant ransport via an on-surface-reaction in the microchannel, various pairs of electrodes under Alternating current (AC) are used and the effects of different arrangements and positions on flow structure, temperature and concentration fields, were investigated. In addition, the comparison with earliest results shows a good agreement.
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spelling doaj.art-a358afc96012407992ba4c9fc8b630b42022-12-21T18:55:18ZengElsevierAlexandria Engineering Journal1110-01682020-06-0159316491659Numerical simulation of a microfluidic biosensor for C-reactive protein detection into a microchannel with considering electrothermal effectHassnia Hajji0Lioua Kolsi1Kaouther Ghachem2Chemseddine Maatki3Mohamed Naceur Borjini4Research Laboratory of Metrology and Energy Systems, LR18ES21, National Engineering School, University of Monastir, TunisiaDepartment of Mechanical Engineering, College of Engineering, Hai’l University, Hai’l City, Saudi Arabia; Corresponding authors.Department of Industrial Engineering and Systems, College of Engineering, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia; Research Laboratory of Metrology and Energy Systems, LR18ES21, National Engineering School, University of Monastir, Tunisia; Corresponding authors.Department of Mechanical Engineering, College of Engineering, Al Imam Mohammad Ibn Saud Islamic University, Riyadh, Saudi ArabiaResearch Laboratory of Metrology and Energy Systems, LR18ES21, National Engineering School, University of Monastir, TunisiaThe performance enhancement of an electrothermal effect-based biosensor is studied numerically in this research. Indeed, the study of a microfluidic biosensor is used to detect the C-reactive protein into a microchannel with considering electrothermal effect. In the presence of the electrical field, the produced Joule effect gives rise to a temperature gradient and causes homogeneities of electric permittivity and conductivity allowing the generation of flow motions. To improve the rate of reactant ransport via an on-surface-reaction in the microchannel, various pairs of electrodes under Alternating current (AC) are used and the effects of different arrangements and positions on flow structure, temperature and concentration fields, were investigated. In addition, the comparison with earliest results shows a good agreement.http://www.sciencedirect.com/science/article/pii/S1110016820301538MicrochannelNumerical studyBiosensorAC electrothermal
spellingShingle Hassnia Hajji
Lioua Kolsi
Kaouther Ghachem
Chemseddine Maatki
Mohamed Naceur Borjini
Numerical simulation of a microfluidic biosensor for C-reactive protein detection into a microchannel with considering electrothermal effect
Alexandria Engineering Journal
Microchannel
Numerical study
Biosensor
AC electrothermal
title Numerical simulation of a microfluidic biosensor for C-reactive protein detection into a microchannel with considering electrothermal effect
title_full Numerical simulation of a microfluidic biosensor for C-reactive protein detection into a microchannel with considering electrothermal effect
title_fullStr Numerical simulation of a microfluidic biosensor for C-reactive protein detection into a microchannel with considering electrothermal effect
title_full_unstemmed Numerical simulation of a microfluidic biosensor for C-reactive protein detection into a microchannel with considering electrothermal effect
title_short Numerical simulation of a microfluidic biosensor for C-reactive protein detection into a microchannel with considering electrothermal effect
title_sort numerical simulation of a microfluidic biosensor for c reactive protein detection into a microchannel with considering electrothermal effect
topic Microchannel
Numerical study
Biosensor
AC electrothermal
url http://www.sciencedirect.com/science/article/pii/S1110016820301538
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