Compartmentalized Immune Response in Leishmaniasis: Changing Patterns throughout the Disease.

Compartmentalized Immune Response in Leishmaniasis: Changing Patterns throughout the Disease.

Visceral leishmaniasis (VL) is characterized by loss of T-cell responsiveness and absence of Leishmania-specific IFN-γ production by peripheral blood mononuclear cells. However, the expressions of IFN-γ and TNF-α are up-regulated in the tissues and plasma of VL patients. There is a paucity of inform...

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Main Authors: Alhelí Rodríguez-Cortés, Eugenia Carrillo, Susanna Martorell, Felicitat Todolí, Ana Ojeda, Alba Martínez-Flórez, Alicia Urniza, Javier Moreno, Jordi Alberola
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4865036?pdf=render

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