EFFICIENCY OF IMMUNOCORRECTION IN СHRONIC VIRAL HEPATITIS C PATIENTS TREATED BY ANTIVIRALS

Abstract. Chronic hepatitis C antiviral therapy should be followed by immune rehabilitation measures directed to T-cell immunity stimulation and elimination of circulating immune complexes. The dynamics of concentrations of molecular fractions of circulating immune complexes and immunoglobulins has...

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Main Authors: L. P. Sklyar, E. V. Markelova, I. S. Gorelova
Format: Article
Language:Russian
Published: Sankt-Peterburg : NIIÈM imeni Pastera 2014-07-01
Series:Инфекция и иммунитет
Subjects:
Online Access:https://www.iimmun.ru/iimm/article/view/124
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author L. P. Sklyar
E. V. Markelova
I. S. Gorelova
author_facet L. P. Sklyar
E. V. Markelova
I. S. Gorelova
author_sort L. P. Sklyar
collection DOAJ
description Abstract. Chronic hepatitis C antiviral therapy should be followed by immune rehabilitation measures directed to T-cell immunity stimulation and elimination of circulating immune complexes. The dynamics of concentrations of molecular fractions of circulating immune complexes and immunoglobulins has been studied. Moreover, phagocytosis indices were evaluated during combined antiviral therapy by standard PEG-interferon and ribavirin and immuno correction drag Ronkoleukin. Application of Ronkoleukin in combination with antiviral therapy determines possibilities to optimize existing treatment protocols of chronic hepatitis C.
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spelling doaj.art-a3659fb6a5e140c0865119fbb62b1ebf2023-01-02T00:08:17ZrusSankt-Peterburg : NIIÈM imeni PasteraИнфекция и иммунитет2220-76192313-73982014-07-0131596410.15789/2220-7619-2013-1-59-64124EFFICIENCY OF IMMUNOCORRECTION IN СHRONIC VIRAL HEPATITIS C PATIENTS TREATED BY ANTIVIRALSL. P. Sklyar0E. V. Markelova1I. S. Gorelova2ГБОУ ВПО Владивостокский государственный медицинский университет МЗ РФГБОУ ВПО Владивостокский государственный медицинский университет МЗ РФГБОУ ВПО Владивостокский государственный медицинский университет МЗ РФAbstract. Chronic hepatitis C antiviral therapy should be followed by immune rehabilitation measures directed to T-cell immunity stimulation and elimination of circulating immune complexes. The dynamics of concentrations of molecular fractions of circulating immune complexes and immunoglobulins has been studied. Moreover, phagocytosis indices were evaluated during combined antiviral therapy by standard PEG-interferon and ribavirin and immuno correction drag Ronkoleukin. Application of Ronkoleukin in combination with antiviral therapy determines possibilities to optimize existing treatment protocols of chronic hepatitis C.https://www.iimmun.ru/iimm/article/view/124сhronic viral hepatitis cantiviral therapyimmune rehabilitation
spellingShingle L. P. Sklyar
E. V. Markelova
I. S. Gorelova
EFFICIENCY OF IMMUNOCORRECTION IN СHRONIC VIRAL HEPATITIS C PATIENTS TREATED BY ANTIVIRALS
Инфекция и иммунитет
сhronic viral hepatitis c
antiviral therapy
immune rehabilitation
title EFFICIENCY OF IMMUNOCORRECTION IN СHRONIC VIRAL HEPATITIS C PATIENTS TREATED BY ANTIVIRALS
title_full EFFICIENCY OF IMMUNOCORRECTION IN СHRONIC VIRAL HEPATITIS C PATIENTS TREATED BY ANTIVIRALS
title_fullStr EFFICIENCY OF IMMUNOCORRECTION IN СHRONIC VIRAL HEPATITIS C PATIENTS TREATED BY ANTIVIRALS
title_full_unstemmed EFFICIENCY OF IMMUNOCORRECTION IN СHRONIC VIRAL HEPATITIS C PATIENTS TREATED BY ANTIVIRALS
title_short EFFICIENCY OF IMMUNOCORRECTION IN СHRONIC VIRAL HEPATITIS C PATIENTS TREATED BY ANTIVIRALS
title_sort efficiency of immunocorrection in сhronic viral hepatitis c patients treated by antivirals
topic сhronic viral hepatitis c
antiviral therapy
immune rehabilitation
url https://www.iimmun.ru/iimm/article/view/124
work_keys_str_mv AT lpsklyar efficiencyofimmunocorrectioninshronicviralhepatitiscpatientstreatedbyantivirals
AT evmarkelova efficiencyofimmunocorrectioninshronicviralhepatitiscpatientstreatedbyantivirals
AT isgorelova efficiencyofimmunocorrectioninshronicviralhepatitiscpatientstreatedbyantivirals