EFFICIENCY OF IMMUNOCORRECTION IN СHRONIC VIRAL HEPATITIS C PATIENTS TREATED BY ANTIVIRALS
Abstract. Chronic hepatitis C antiviral therapy should be followed by immune rehabilitation measures directed to T-cell immunity stimulation and elimination of circulating immune complexes. The dynamics of concentrations of molecular fractions of circulating immune complexes and immunoglobulins has...
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Format: | Article |
Language: | Russian |
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Sankt-Peterburg : NIIÈM imeni Pastera
2014-07-01
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Series: | Инфекция и иммунитет |
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Online Access: | https://www.iimmun.ru/iimm/article/view/124 |
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author | L. P. Sklyar E. V. Markelova I. S. Gorelova |
author_facet | L. P. Sklyar E. V. Markelova I. S. Gorelova |
author_sort | L. P. Sklyar |
collection | DOAJ |
description | Abstract. Chronic hepatitis C antiviral therapy should be followed by immune rehabilitation measures directed to T-cell immunity stimulation and elimination of circulating immune complexes. The dynamics of concentrations of molecular fractions of circulating immune complexes and immunoglobulins has been studied. Moreover, phagocytosis indices were evaluated during combined antiviral therapy by standard PEG-interferon and ribavirin and immuno correction drag Ronkoleukin. Application of Ronkoleukin in combination with antiviral therapy determines possibilities to optimize existing treatment protocols of chronic hepatitis C. |
first_indexed | 2024-04-11T03:58:41Z |
format | Article |
id | doaj.art-a3659fb6a5e140c0865119fbb62b1ebf |
institution | Directory Open Access Journal |
issn | 2220-7619 2313-7398 |
language | Russian |
last_indexed | 2024-04-11T03:58:41Z |
publishDate | 2014-07-01 |
publisher | Sankt-Peterburg : NIIÈM imeni Pastera |
record_format | Article |
series | Инфекция и иммунитет |
spelling | doaj.art-a3659fb6a5e140c0865119fbb62b1ebf2023-01-02T00:08:17ZrusSankt-Peterburg : NIIÈM imeni PasteraИнфекция и иммунитет2220-76192313-73982014-07-0131596410.15789/2220-7619-2013-1-59-64124EFFICIENCY OF IMMUNOCORRECTION IN СHRONIC VIRAL HEPATITIS C PATIENTS TREATED BY ANTIVIRALSL. P. Sklyar0E. V. Markelova1I. S. Gorelova2ГБОУ ВПО Владивостокский государственный медицинский университет МЗ РФГБОУ ВПО Владивостокский государственный медицинский университет МЗ РФГБОУ ВПО Владивостокский государственный медицинский университет МЗ РФAbstract. Chronic hepatitis C antiviral therapy should be followed by immune rehabilitation measures directed to T-cell immunity stimulation and elimination of circulating immune complexes. The dynamics of concentrations of molecular fractions of circulating immune complexes and immunoglobulins has been studied. Moreover, phagocytosis indices were evaluated during combined antiviral therapy by standard PEG-interferon and ribavirin and immuno correction drag Ronkoleukin. Application of Ronkoleukin in combination with antiviral therapy determines possibilities to optimize existing treatment protocols of chronic hepatitis C.https://www.iimmun.ru/iimm/article/view/124сhronic viral hepatitis cantiviral therapyimmune rehabilitation |
spellingShingle | L. P. Sklyar E. V. Markelova I. S. Gorelova EFFICIENCY OF IMMUNOCORRECTION IN СHRONIC VIRAL HEPATITIS C PATIENTS TREATED BY ANTIVIRALS Инфекция и иммунитет сhronic viral hepatitis c antiviral therapy immune rehabilitation |
title | EFFICIENCY OF IMMUNOCORRECTION IN СHRONIC VIRAL HEPATITIS C PATIENTS TREATED BY ANTIVIRALS |
title_full | EFFICIENCY OF IMMUNOCORRECTION IN СHRONIC VIRAL HEPATITIS C PATIENTS TREATED BY ANTIVIRALS |
title_fullStr | EFFICIENCY OF IMMUNOCORRECTION IN СHRONIC VIRAL HEPATITIS C PATIENTS TREATED BY ANTIVIRALS |
title_full_unstemmed | EFFICIENCY OF IMMUNOCORRECTION IN СHRONIC VIRAL HEPATITIS C PATIENTS TREATED BY ANTIVIRALS |
title_short | EFFICIENCY OF IMMUNOCORRECTION IN СHRONIC VIRAL HEPATITIS C PATIENTS TREATED BY ANTIVIRALS |
title_sort | efficiency of immunocorrection in сhronic viral hepatitis c patients treated by antivirals |
topic | сhronic viral hepatitis c antiviral therapy immune rehabilitation |
url | https://www.iimmun.ru/iimm/article/view/124 |
work_keys_str_mv | AT lpsklyar efficiencyofimmunocorrectioninshronicviralhepatitiscpatientstreatedbyantivirals AT evmarkelova efficiencyofimmunocorrectioninshronicviralhepatitiscpatientstreatedbyantivirals AT isgorelova efficiencyofimmunocorrectioninshronicviralhepatitiscpatientstreatedbyantivirals |