Genetically engineered CXCR4-modified exosomes for delivery of miR-126 mimics to macrophages alleviate periodontitis

Genetically engineered CXCR4-modified exosomes for delivery of miR-126 mimics to macrophages alleviate periodontitis

Abstract Biofilm-related diseases are a group of diseases that tolerate antimicrobial chemotherapies and therefore are refractory to treatment. Periodontitis, a non-device chronic biofilm disease induced by dental plaque, can serve as an excellent in vivo model to study the important effects of host...

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Bibliographic Details
Main Authors: Haotian Luo, Danying Chen, Ruoyu Li, Runze Li, Yungshan Teng, Yang Cao, Xuenong Zou, Weicai Wang, Chen Zhou
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Journal of Nanobiotechnology
Subjects:
Biofilm diseases
Targeted delivery
Immunomodulation
Gene therapy
Extracellular vesicles
Online Access:https://doi.org/10.1186/s12951-023-01863-w

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