Potential Epigenetic Regulation in the Germinal Center Reaction of Lymphoid Tissues in HIV/SIV Infection

The production of high-affinity and broadly neutralizing antibodies plays a key role in the defense against pathogens. These antibody responses require effective germinal center (GC) reaction within anatomical niches of GCs, where follicular helper T (Tfh) cells provide cognate help to B cells for T...

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Dades bibliogràfiques
Autors principals: Xiaolei Wang, Huanbin Xu
Format: Article
Idioma:English
Publicat: Frontiers Media S.A. 2018-02-01
Col·lecció:Frontiers in Immunology
Matèries:
Accés en línia:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00159/full