Potential Epigenetic Regulation in the Germinal Center Reaction of Lymphoid Tissues in HIV/SIV Infection

The production of high-affinity and broadly neutralizing antibodies plays a key role in the defense against pathogens. These antibody responses require effective germinal center (GC) reaction within anatomical niches of GCs, where follicular helper T (Tfh) cells provide cognate help to B cells for T...

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Main Authors: Xiaolei Wang, Huanbin Xu
פורמט: Article
שפה:English
יצא לאור: Frontiers Media S.A. 2018-02-01
סדרה:Frontiers in Immunology
נושאים:
גישה מקוונת:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00159/full