Heightened inflammasome activation is linked to age-related cognitive impairment in Fischer 344 rats

Heightened inflammasome activation is linked to age-related cognitive impairment in Fischer 344 rats

<p>Abstract</p> <p>Background</p> <p>Members of the mammalian nucleotide binding domain, leucine-rich repeat (LRR)-containing receptor (NLR) family of proteins are key modulators of innate immunity regulating inflammation. Our previous work has shown that among the memb...

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Bibliographic Details
Main Authors: Mawhinney Lana J, de Vaccari Rivero Juan, Dale Gordon A, Keane Robert W, Bramlett Helen M
Format: Article
Language:English
Published: BMC 2011-12-01
Series:BMC Neuroscience
Online Access:http://www.biomedcentral.com/1471-2202/12/123

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