Insulin/Glucose-Responsive Cells Derived from Induced Pluripotent Stem Cells: Disease Modeling and Treatment of Diabetes

Insulin/Glucose-Responsive Cells Derived from Induced Pluripotent Stem Cells: Disease Modeling and Treatment of Diabetes

Type 2 diabetes, characterized by dysfunction of pancreatic β-cells and insulin resistance in peripheral organs, accounts for more than 90% of all diabetes. Despite current developments of new drugs and strategies to prevent/treat diabetes, there is no ideal therapy targeting all aspects of the dise...

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Bibliographic Details
Main Authors: Sevda Gheibi, Tania Singh, Joao Paulo M. C. M. da Cunha, Malin Fex, Hindrik Mulder
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Cells
Subjects:
adipocyte
β-cells
diabetes
hepatocyte
insulin resistance
iPSC
Online Access:https://www.mdpi.com/2073-4409/9/11/2465

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