HDGFL2 cryptic proteins report presence of TDP-43 pathology in neurodegenerative diseases
Abstract This letter demonstrates the potential of novel cryptic proteins resulting from TAR DNA-binding protein 43 (TDP-43) dysfunction as markers of TDP-43 pathology in neurodegenerative diseases.
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2024-03-01
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| Series: | Molecular Neurodegeneration |
| Online Access: | https://doi.org/10.1186/s13024-024-00718-8 |
| _version_ | 1797233272161304576 |
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| author | Anna Calliari Lillian M. Daughrity Ellen A. Albagli Paula Castellanos Otero Mei Yue Karen Jansen-West Naeyma N. Islam Thomas Caulfield Bailey Rawlinson Michael DeTure Casey Cook Neill R. Graff-Radford Gregory S. Day Bradley F. Boeve David S. Knopman Ronald C. Petersen Keith A. Josephs Björn Oskarsson Aaron D. Gitler Dennis W. Dickson Tania F. Gendron Mercedes Prudencio Michael E. Ward Yong-Jie Zhang Leonard Petrucelli |
| author_facet | Anna Calliari Lillian M. Daughrity Ellen A. Albagli Paula Castellanos Otero Mei Yue Karen Jansen-West Naeyma N. Islam Thomas Caulfield Bailey Rawlinson Michael DeTure Casey Cook Neill R. Graff-Radford Gregory S. Day Bradley F. Boeve David S. Knopman Ronald C. Petersen Keith A. Josephs Björn Oskarsson Aaron D. Gitler Dennis W. Dickson Tania F. Gendron Mercedes Prudencio Michael E. Ward Yong-Jie Zhang Leonard Petrucelli |
| author_sort | Anna Calliari |
| collection | DOAJ |
| description | Abstract This letter demonstrates the potential of novel cryptic proteins resulting from TAR DNA-binding protein 43 (TDP-43) dysfunction as markers of TDP-43 pathology in neurodegenerative diseases. |
| first_indexed | 2024-04-24T16:13:32Z |
| format | Article |
| id | doaj.art-a36e0957494842178bf60c68ee7aa96b |
| institution | Directory Open Access Journal |
| issn | 1750-1326 |
| language | English |
| last_indexed | 2024-04-24T16:13:32Z |
| publishDate | 2024-03-01 |
| publisher | BMC |
| record_format | Article |
| series | Molecular Neurodegeneration |
| spelling | doaj.art-a36e0957494842178bf60c68ee7aa96b2024-03-31T11:35:32ZengBMCMolecular Neurodegeneration1750-13262024-03-011911510.1186/s13024-024-00718-8HDGFL2 cryptic proteins report presence of TDP-43 pathology in neurodegenerative diseasesAnna Calliari0Lillian M. Daughrity1Ellen A. Albagli2Paula Castellanos Otero3Mei Yue4Karen Jansen-West5Naeyma N. Islam6Thomas Caulfield7Bailey Rawlinson8Michael DeTure9Casey Cook10Neill R. Graff-Radford11Gregory S. Day12Bradley F. Boeve13David S. Knopman14Ronald C. Petersen15Keith A. Josephs16Björn Oskarsson17Aaron D. Gitler18Dennis W. Dickson19Tania F. Gendron20Mercedes Prudencio21Michael E. Ward22Yong-Jie Zhang23Leonard Petrucelli24Department of Neuroscience, Mayo ClinicDepartment of Neuroscience, Mayo ClinicDepartment of Neuroscience, Mayo ClinicDepartment of Neuroscience, Mayo ClinicDepartment of Neuroscience, Mayo ClinicDepartment of Neuroscience, Mayo ClinicDepartment of Neuroscience, Mayo ClinicDepartment of Neuroscience, Mayo ClinicDepartment of Neuroscience, Mayo ClinicDepartment of Neuroscience, Mayo ClinicDepartment of Neuroscience, Mayo ClinicDepartment of Neurology, Mayo ClinicDepartment of Neurology, Mayo ClinicDepartment of Neurology, Mayo ClinicDepartment of Neurology, Mayo ClinicDepartment of Neurology, Mayo ClinicDepartment of Neurology, Mayo ClinicDepartment of Neurology, Mayo ClinicDepartment of Genetics, Stanford University School of MedicineDepartment of Neuroscience, Mayo ClinicDepartment of Neuroscience, Mayo ClinicDepartment of Neuroscience, Mayo ClinicNational Institute of Neurological Disorders and Stroke, National Institutes of HealthDepartment of Neuroscience, Mayo ClinicDepartment of Neuroscience, Mayo ClinicAbstract This letter demonstrates the potential of novel cryptic proteins resulting from TAR DNA-binding protein 43 (TDP-43) dysfunction as markers of TDP-43 pathology in neurodegenerative diseases.https://doi.org/10.1186/s13024-024-00718-8 |
| spellingShingle | Anna Calliari Lillian M. Daughrity Ellen A. Albagli Paula Castellanos Otero Mei Yue Karen Jansen-West Naeyma N. Islam Thomas Caulfield Bailey Rawlinson Michael DeTure Casey Cook Neill R. Graff-Radford Gregory S. Day Bradley F. Boeve David S. Knopman Ronald C. Petersen Keith A. Josephs Björn Oskarsson Aaron D. Gitler Dennis W. Dickson Tania F. Gendron Mercedes Prudencio Michael E. Ward Yong-Jie Zhang Leonard Petrucelli HDGFL2 cryptic proteins report presence of TDP-43 pathology in neurodegenerative diseases Molecular Neurodegeneration |
| title | HDGFL2 cryptic proteins report presence of TDP-43 pathology in neurodegenerative diseases |
| title_full | HDGFL2 cryptic proteins report presence of TDP-43 pathology in neurodegenerative diseases |
| title_fullStr | HDGFL2 cryptic proteins report presence of TDP-43 pathology in neurodegenerative diseases |
| title_full_unstemmed | HDGFL2 cryptic proteins report presence of TDP-43 pathology in neurodegenerative diseases |
| title_short | HDGFL2 cryptic proteins report presence of TDP-43 pathology in neurodegenerative diseases |
| title_sort | hdgfl2 cryptic proteins report presence of tdp 43 pathology in neurodegenerative diseases |
| url | https://doi.org/10.1186/s13024-024-00718-8 |
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