Anaphylactic shock to vaginal misoprostol: a rare adverse reaction to a frequently used drug
Misoprostol is widely used in daily practice for induction of labor and cervical dilatation prior to intrauterine procedures, including dilatation and curettage or hysteroscopy. Anaphylactic shock to intravaginal misoprostol can occur not only in pregnant women, as reported in 2 previous cases, but...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Korean Society of Obstetrics and Gynecology
2018-09-01
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| Series: | Obstetrics & Gynecology Science |
| Subjects: | |
| Online Access: | http://ogscience.org/upload/pdf/ogs-61-636.pdf |
| _version_ | 1818987110299860992 |
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| author | Hyun Joo Shin Sa Ra Lee A-mi Roh Young-mee Lim Kyung Ah Jeong Hye-Sung Moon Hye Won Chung |
| author_facet | Hyun Joo Shin Sa Ra Lee A-mi Roh Young-mee Lim Kyung Ah Jeong Hye-Sung Moon Hye Won Chung |
| author_sort | Hyun Joo Shin |
| collection | DOAJ |
| description | Misoprostol is widely used in daily practice for induction of labor and cervical dilatation prior to intrauterine procedures, including dilatation and curettage or hysteroscopy. Anaphylactic shock to intravaginal misoprostol can occur not only in pregnant women, as reported in 2 previous cases, but also in a non-pregnant, perimenopausal woman, as in the case described herein. A 49-year-old woman received vaginal misoprostol for cervical ripening prior to hysteroscopic myomectomy and experienced anaphylactic shock. Two 400 μg doses of misoprostol 6 hours apart caused uncontrolled shaking and high fever followed by shock. In conclusion, the possibility of anaphylactic shock should be considered in patients with sudden hypotension following misoprostol administration. Prompt identification and management are crucial to prevent morbidity and mortality following an anaphylactic shock to misoprostol. |
| first_indexed | 2024-12-20T19:01:28Z |
| format | Article |
| id | doaj.art-a373fff4ceec48d0aa19358ba8872726 |
| institution | Directory Open Access Journal |
| issn | 2287-8572 2287-8580 |
| language | English |
| last_indexed | 2024-12-20T19:01:28Z |
| publishDate | 2018-09-01 |
| publisher | Korean Society of Obstetrics and Gynecology |
| record_format | Article |
| series | Obstetrics & Gynecology Science |
| spelling | doaj.art-a373fff4ceec48d0aa19358ba88727262022-12-21T19:29:23ZengKorean Society of Obstetrics and GynecologyObstetrics & Gynecology Science2287-85722287-85802018-09-0161563664010.5468/ogs.2018.61.5.636535Anaphylactic shock to vaginal misoprostol: a rare adverse reaction to a frequently used drugHyun Joo Shin0Sa Ra Lee1A-mi Roh2Young-mee Lim3Kyung Ah Jeong4Hye-Sung Moon5Hye Won Chung6Department of Obstetrics and Gynecology, College of Medicine, Ewha Womans University, Seoul, .KoreaDepartment of Obstetrics and Gynecology, College of Medicine, Ewha Womans University, Seoul, .KoreaDepartment of Obstetrics and Gynecology, College of Medicine, Ewha Womans University, Seoul, .KoreaDepartment of Obstetrics and Gynecology, College of Medicine, Ewha Womans University, Seoul, .KoreaDepartment of Obstetrics and Gynecology, College of Medicine, Ewha Womans University, Seoul, .KoreaDepartment of Obstetrics and Gynecology, College of Medicine, Ewha Womans University, Seoul, .KoreaDepartment of Obstetrics and Gynecology, College of Medicine, Ewha Womans University, Seoul, .KoreaMisoprostol is widely used in daily practice for induction of labor and cervical dilatation prior to intrauterine procedures, including dilatation and curettage or hysteroscopy. Anaphylactic shock to intravaginal misoprostol can occur not only in pregnant women, as reported in 2 previous cases, but also in a non-pregnant, perimenopausal woman, as in the case described herein. A 49-year-old woman received vaginal misoprostol for cervical ripening prior to hysteroscopic myomectomy and experienced anaphylactic shock. Two 400 μg doses of misoprostol 6 hours apart caused uncontrolled shaking and high fever followed by shock. In conclusion, the possibility of anaphylactic shock should be considered in patients with sudden hypotension following misoprostol administration. Prompt identification and management are crucial to prevent morbidity and mortality following an anaphylactic shock to misoprostol.http://ogscience.org/upload/pdf/ogs-61-636.pdfanaphylaxisshockhysteroscopymisoprostol |
| spellingShingle | Hyun Joo Shin Sa Ra Lee A-mi Roh Young-mee Lim Kyung Ah Jeong Hye-Sung Moon Hye Won Chung Anaphylactic shock to vaginal misoprostol: a rare adverse reaction to a frequently used drug Obstetrics & Gynecology Science anaphylaxis shock hysteroscopy misoprostol |
| title | Anaphylactic shock to vaginal misoprostol: a rare adverse reaction to a frequently used drug |
| title_full | Anaphylactic shock to vaginal misoprostol: a rare adverse reaction to a frequently used drug |
| title_fullStr | Anaphylactic shock to vaginal misoprostol: a rare adverse reaction to a frequently used drug |
| title_full_unstemmed | Anaphylactic shock to vaginal misoprostol: a rare adverse reaction to a frequently used drug |
| title_short | Anaphylactic shock to vaginal misoprostol: a rare adverse reaction to a frequently used drug |
| title_sort | anaphylactic shock to vaginal misoprostol a rare adverse reaction to a frequently used drug |
| topic | anaphylaxis shock hysteroscopy misoprostol |
| url | http://ogscience.org/upload/pdf/ogs-61-636.pdf |
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