Prognostic value of heart failure biomarkers in the assessment of cardiac dysfunction in the fetus and newborn

The assessment of the cardiac function of the fetus and hemodynamic stabilization of the newborn in the postnatal period is one of the most important tasks of modern perinatology. Understanding the pathophysiological mechanisms, the basis of the myocardial dysfunction in both the fetus and the newbo...

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Main Authors: O. A. Savchenko, E. B. Pavlinova, N. A. Polyanskaya, I. A. Kirshina, A. A. Gubich, Yu. V. Chuprik
Format: Article
Language:Russian
Published: Ltd. “The National Academy of Pediatric Science and Innovation” 2021-05-01
Series:Rossijskij Vestnik Perinatologii i Pediatrii
Subjects:
Online Access:https://www.ped-perinatology.ru/jour/article/view/1372
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author O. A. Savchenko
E. B. Pavlinova
N. A. Polyanskaya
I. A. Kirshina
A. A. Gubich
Yu. V. Chuprik
author_facet O. A. Savchenko
E. B. Pavlinova
N. A. Polyanskaya
I. A. Kirshina
A. A. Gubich
Yu. V. Chuprik
author_sort O. A. Savchenko
collection DOAJ
description The assessment of the cardiac function of the fetus and hemodynamic stabilization of the newborn in the postnatal period is one of the most important tasks of modern perinatology. Understanding the pathophysiological mechanisms, the basis of the myocardial dysfunction in both the fetus and the newborn, can help to develop preventive measures and change the therapeutic approach to this category of children. This review highlights the problems of the disruption of the mechanisms of interregulation in the fetal heart and placenta, as well as the diagnostic possibilities of modern biomarkers of cardiovascular dysfunction – troponins, N-terminal precursor of brain natriuretic peptide and soluble type 2 tumor suppressor – in fetal and newborn.
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spelling doaj.art-a37a9a6d1dfe47229af01a9e479cf5aa2023-03-13T09:12:50ZrusLtd. “The National Academy of Pediatric Science and Innovation”Rossijskij Vestnik Perinatologii i Pediatrii1027-40652500-22282021-05-01662414810.21508/1027-4065-2021-66-2-41-481024Prognostic value of heart failure biomarkers in the assessment of cardiac dysfunction in the fetus and newbornO. A. Savchenko0E. B. Pavlinova1N. A. Polyanskaya2I. A. Kirshina3A. A. Gubich4Yu. V. Chuprik5ФГБОУ ВО «Омский государственный медицинский университет» Минздрава РоссииФГБОУ ВО «Омский государственный медицинский университет» Минздрава РоссииФГБОУ ВО «Омский государственный медицинский университет» Минздрава РоссииФГБОУ ВО «Омский государственный медицинский университет» Минздрава РоссииФГБОУ ВО «Омский государственный медицинский университет» Минздрава РоссииБУЗОО «Городской клинический перинатальный центр»The assessment of the cardiac function of the fetus and hemodynamic stabilization of the newborn in the postnatal period is one of the most important tasks of modern perinatology. Understanding the pathophysiological mechanisms, the basis of the myocardial dysfunction in both the fetus and the newborn, can help to develop preventive measures and change the therapeutic approach to this category of children. This review highlights the problems of the disruption of the mechanisms of interregulation in the fetal heart and placenta, as well as the diagnostic possibilities of modern biomarkers of cardiovascular dysfunction – troponins, N-terminal precursor of brain natriuretic peptide and soluble type 2 tumor suppressor – in fetal and newborn.https://www.ped-perinatology.ru/jour/article/view/1372плодноворожденныйгемодинамикасердечная недостаточностьбиомаркеры
spellingShingle O. A. Savchenko
E. B. Pavlinova
N. A. Polyanskaya
I. A. Kirshina
A. A. Gubich
Yu. V. Chuprik
Prognostic value of heart failure biomarkers in the assessment of cardiac dysfunction in the fetus and newborn
Rossijskij Vestnik Perinatologii i Pediatrii
плод
новорожденный
гемодинамика
сердечная недостаточность
биомаркеры
title Prognostic value of heart failure biomarkers in the assessment of cardiac dysfunction in the fetus and newborn
title_full Prognostic value of heart failure biomarkers in the assessment of cardiac dysfunction in the fetus and newborn
title_fullStr Prognostic value of heart failure biomarkers in the assessment of cardiac dysfunction in the fetus and newborn
title_full_unstemmed Prognostic value of heart failure biomarkers in the assessment of cardiac dysfunction in the fetus and newborn
title_short Prognostic value of heart failure biomarkers in the assessment of cardiac dysfunction in the fetus and newborn
title_sort prognostic value of heart failure biomarkers in the assessment of cardiac dysfunction in the fetus and newborn
topic плод
новорожденный
гемодинамика
сердечная недостаточность
биомаркеры
url https://www.ped-perinatology.ru/jour/article/view/1372
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AT ebpavlinova prognosticvalueofheartfailurebiomarkersintheassessmentofcardiacdysfunctioninthefetusandnewborn
AT napolyanskaya prognosticvalueofheartfailurebiomarkersintheassessmentofcardiacdysfunctioninthefetusandnewborn
AT iakirshina prognosticvalueofheartfailurebiomarkersintheassessmentofcardiacdysfunctioninthefetusandnewborn
AT aagubich prognosticvalueofheartfailurebiomarkersintheassessmentofcardiacdysfunctioninthefetusandnewborn
AT yuvchuprik prognosticvalueofheartfailurebiomarkersintheassessmentofcardiacdysfunctioninthefetusandnewborn