Enterovirus A71 Proteins: Structure and Function
Enterovirus A71 (EV-A71) infection has grown to become a serious threat to global public health. It is one of the major causes of hand, foot, and mouth disease (HFMD) in infants and young children. EV-A71 can also infect the central nervous system (CNS) and induce diverse neurological complications,...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2018-02-01
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| Series: | Frontiers in Microbiology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/article/10.3389/fmicb.2018.00286/full |
| _version_ | 1818528321845067776 |
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| author | Jingjing Yuan Jingjing Yuan Li Shen Jing Wu Xinran Zou Jiaqi Gu Jianguo Chen Lingxiang Mao |
| author_facet | Jingjing Yuan Jingjing Yuan Li Shen Jing Wu Xinran Zou Jiaqi Gu Jianguo Chen Lingxiang Mao |
| author_sort | Jingjing Yuan |
| collection | DOAJ |
| description | Enterovirus A71 (EV-A71) infection has grown to become a serious threat to global public health. It is one of the major causes of hand, foot, and mouth disease (HFMD) in infants and young children. EV-A71 can also infect the central nervous system (CNS) and induce diverse neurological complications, such as brainstem encephalitis, aseptic meningitis, and acute flaccid paralysis, or even death. Viral proteins play a crucial role in EV-A71 infection. Many recent studies have discussed the structure and function of EV-A71 proteins, and the findings reported will definitely aid the development of vaccines and therapeutic approaches. This article reviews the progress in the research on the structure and function of EV-A71 proteins. Available literature can provide a basis for studying the pathogenesis of EV-A71 infection in detail. |
| first_indexed | 2024-12-11T06:48:16Z |
| format | Article |
| id | doaj.art-a37cd001fae246d39950236037c22d6e |
| institution | Directory Open Access Journal |
| issn | 1664-302X |
| language | English |
| last_indexed | 2024-12-11T06:48:16Z |
| publishDate | 2018-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Microbiology |
| spelling | doaj.art-a37cd001fae246d39950236037c22d6e2022-12-22T01:17:01ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2018-02-01910.3389/fmicb.2018.00286338696Enterovirus A71 Proteins: Structure and FunctionJingjing Yuan0Jingjing Yuan1Li Shen2Jing Wu3Xinran Zou4Jiaqi Gu5Jianguo Chen6Lingxiang Mao7Department of Laboratory Medicine, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, ChinaClinical Laboratory, Danyang People's Hospital, Jiangsu, ChinaClinical Laboratory, Zhenjiang Center for Disease Control and Prevention, Jiangsu, ChinaInstitute of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, ChinaInstitute of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, ChinaInstitute of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, ChinaDepartment of Laboratory Medicine, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, ChinaDepartment of Laboratory Medicine, The Affiliated People's Hospital, Jiangsu University, Zhenjiang, ChinaEnterovirus A71 (EV-A71) infection has grown to become a serious threat to global public health. It is one of the major causes of hand, foot, and mouth disease (HFMD) in infants and young children. EV-A71 can also infect the central nervous system (CNS) and induce diverse neurological complications, such as brainstem encephalitis, aseptic meningitis, and acute flaccid paralysis, or even death. Viral proteins play a crucial role in EV-A71 infection. Many recent studies have discussed the structure and function of EV-A71 proteins, and the findings reported will definitely aid the development of vaccines and therapeutic approaches. This article reviews the progress in the research on the structure and function of EV-A71 proteins. Available literature can provide a basis for studying the pathogenesis of EV-A71 infection in detail.http://journal.frontiersin.org/article/10.3389/fmicb.2018.00286/fullenterovirus-A71proteinstructurefunctionepitope |
| spellingShingle | Jingjing Yuan Jingjing Yuan Li Shen Jing Wu Xinran Zou Jiaqi Gu Jianguo Chen Lingxiang Mao Enterovirus A71 Proteins: Structure and Function Frontiers in Microbiology enterovirus-A71 protein structure function epitope |
| title | Enterovirus A71 Proteins: Structure and Function |
| title_full | Enterovirus A71 Proteins: Structure and Function |
| title_fullStr | Enterovirus A71 Proteins: Structure and Function |
| title_full_unstemmed | Enterovirus A71 Proteins: Structure and Function |
| title_short | Enterovirus A71 Proteins: Structure and Function |
| title_sort | enterovirus a71 proteins structure and function |
| topic | enterovirus-A71 protein structure function epitope |
| url | http://journal.frontiersin.org/article/10.3389/fmicb.2018.00286/full |
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