Platelets from glioblastoma patients promote angiogenesis of tumor endothelial cells and exhibit increased VEGF content and release

Platelets from glioblastoma patients promote angiogenesis of tumor endothelial cells and exhibit increased VEGF content and release

Glioblastoma multiforme (GBM) is the most common and fatal intracranial cancer in humans and exhibits intense and aberrant angiogenesis that sustains its malignancy and involves several angiogenic signals. Among them, vascular endothelial growth factor (VEGF) plays a key role and is overexpressed in...

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Bibliographic Details
Main Authors: Clara Di Vito, Stefania Elena Navone, Giovanni Marfia, Loubna Abdel Hadi, Maria Elisa Mancuso, Alessandro Pecci, Francesco Maria Crisà, Valeria Berno, Paolo Rampini, Rolando Campanella, Laura Riboni
Format: Article
Language:English
Published: Taylor & Francis Group 2017-08-01
Series:Platelets
Subjects:
glioblastoma
platelets
tumor endothelial cells
vegf
Online Access:http://dx.doi.org/10.1080/09537104.2016.1247208

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