Vildagliptin induced cutaneous leukocytoclastic vasculitis: A case report

Vildagliptin is a new generation theurapeutic agent of diabetes mellitus which belongs to dipeptidyl peptidase-IV inhibitor class acting via the incretin hormone system. It has moderate glycemic efficacy, a low propensity of causing hypoglycaemia and it is weight neutral. Overall, Dipeptidyl peptida...

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Main Authors: Serhat Sayin, Ethem Omeroglu, Semra Aslan Bilgin
Format: Article
Language:English
Published: Society of Turaz Bilim 2018-03-01
Series:Medicine Science
Subjects:
Online Access:http://www.ejmanager.com/fulltextpdf.php?mno=265066
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author Serhat Sayin
Ethem Omeroglu
Semra Aslan Bilgin
author_facet Serhat Sayin
Ethem Omeroglu
Semra Aslan Bilgin
author_sort Serhat Sayin
collection DOAJ
description Vildagliptin is a new generation theurapeutic agent of diabetes mellitus which belongs to dipeptidyl peptidase-IV inhibitor class acting via the incretin hormone system. It has moderate glycemic efficacy, a low propensity of causing hypoglycaemia and it is weight neutral. Overall, Dipeptidyl peptidase-4 (DPP-4) inhibitors are well tolerated. The use of DPP-4 inhibitors has been associated with a slightly increased risk of upper respiratory tract infections. In this article, we report a case of cutaneous leukocytoclastic vasculitis due to probable vildagliptin usage. Vildagliptin which is associated with cutaneous leukocytoclastic vasculitis was not described in the literature before. Physical examination revealed skin rash in the abdomen and thigh region in our patients due to use of the drug. Discontinuation of the drug eliminated the skin rash immediately. [Med-Science 2018; 7(1.000): 235-237]
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spelling doaj.art-a384dc58bf8f49c38228c9550d36882a2024-02-03T06:40:37ZengSociety of Turaz BilimMedicine Science2147-06342018-03-017123523710.5455/medscience.2017.06.8691265066Vildagliptin induced cutaneous leukocytoclastic vasculitis: A case reportSerhat Sayin0Ethem OmerogluSemra Aslan BilginDepartment of Internal Medicine, Training and Research Hospital, Aksaray University, Aksaray, Turkey Department of Pathology, Training and Research Hospital, Health Sciences University, Konya, Turkey Department of Dermatology, Training and Research Hospital, Health Sciences University, Konya, TurkeyVildagliptin is a new generation theurapeutic agent of diabetes mellitus which belongs to dipeptidyl peptidase-IV inhibitor class acting via the incretin hormone system. It has moderate glycemic efficacy, a low propensity of causing hypoglycaemia and it is weight neutral. Overall, Dipeptidyl peptidase-4 (DPP-4) inhibitors are well tolerated. The use of DPP-4 inhibitors has been associated with a slightly increased risk of upper respiratory tract infections. In this article, we report a case of cutaneous leukocytoclastic vasculitis due to probable vildagliptin usage. Vildagliptin which is associated with cutaneous leukocytoclastic vasculitis was not described in the literature before. Physical examination revealed skin rash in the abdomen and thigh region in our patients due to use of the drug. Discontinuation of the drug eliminated the skin rash immediately. [Med-Science 2018; 7(1.000): 235-237]http://www.ejmanager.com/fulltextpdf.php?mno=265066VildagliptinVasculitisdiabetes mellitus
spellingShingle Serhat Sayin
Ethem Omeroglu
Semra Aslan Bilgin
Vildagliptin induced cutaneous leukocytoclastic vasculitis: A case report
Medicine Science
Vildagliptin
Vasculitis
diabetes mellitus
title Vildagliptin induced cutaneous leukocytoclastic vasculitis: A case report
title_full Vildagliptin induced cutaneous leukocytoclastic vasculitis: A case report
title_fullStr Vildagliptin induced cutaneous leukocytoclastic vasculitis: A case report
title_full_unstemmed Vildagliptin induced cutaneous leukocytoclastic vasculitis: A case report
title_short Vildagliptin induced cutaneous leukocytoclastic vasculitis: A case report
title_sort vildagliptin induced cutaneous leukocytoclastic vasculitis a case report
topic Vildagliptin
Vasculitis
diabetes mellitus
url http://www.ejmanager.com/fulltextpdf.php?mno=265066
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