Comparative analysis of the association between traditional and lipid-related obesity indicators and isolated systolic hypertension
Abstract Background Obesity is a well-known modified risk factor for isolated systolic hypertension (ISH), but evidence is lacking regarding whether the combination of anthropometric and lipid indicators could strengthen their correlation with ISH. Therefore, we compared the association of body mass...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2022-03-01
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| Series: | BMC Cardiovascular Disorders |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12872-022-02564-2 |
| _version_ | 1811331910538887168 |
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| author | Jian Dong Qian Xiao Mei Li Dong Shui Chen Jian Qin Zhu Xing Zhen Liu |
| author_facet | Jian Dong Qian Xiao Mei Li Dong Shui Chen Jian Qin Zhu Xing Zhen Liu |
| author_sort | Jian Dong Qian |
| collection | DOAJ |
| description | Abstract Background Obesity is a well-known modified risk factor for isolated systolic hypertension (ISH), but evidence is lacking regarding whether the combination of anthropometric and lipid indicators could strengthen their correlation with ISH. Therefore, we compared the association of body mass index (BMI), waist circumference (WC), waist-to-hip ratio (WHR), waist-to-height ratio (WHtR), visceral adiposity index (VAI), lipid accumulation product index (LAP), and cardiometabolic index (CMI) with ISH. Methods A total of 106,248 adults who received routine health screening and did not have diastolic blood pressure ≥ 90 mmHg were recruited in this cross-sectional study. The associations between these indicators and ISH were evaluated using multivariate regression. Results Each standard deviation (SD) increase in traditional obesity indicators (especially WHR and WHtR) had significantly higher multivariate-adjusted odds ratios (ORs) than each SD increase in lipid-related obesity indicators. In addition, multivariate-adjusted ORs for ISH in the third (vs. the first) tertile of traditional obesity indicators were also significantly higher than those of lipid-related indicators. Moreover, traditional obesity indicators exhibited a higher area under the ROC curve for discriminating ISH than lipid-related obesity indicators. Conclusions Traditional obesity indicators were more strongly associated with ISH than lipid-related obesity indicators among Chinese adults. |
| first_indexed | 2024-04-13T16:28:55Z |
| format | Article |
| id | doaj.art-a3864a58c03547a6af860d68d91bc19c |
| institution | Directory Open Access Journal |
| issn | 1471-2261 |
| language | English |
| last_indexed | 2024-04-13T16:28:55Z |
| publishDate | 2022-03-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Cardiovascular Disorders |
| spelling | doaj.art-a3864a58c03547a6af860d68d91bc19c2022-12-22T02:39:40ZengBMCBMC Cardiovascular Disorders1471-22612022-03-012211810.1186/s12872-022-02564-2Comparative analysis of the association between traditional and lipid-related obesity indicators and isolated systolic hypertensionJian Dong Qian0Xiao Mei Li1Dong Shui Chen2Jian Qin Zhu3Xing Zhen Liu4Department of Cardiology, Jingjiang People’s HospitalDepartment of Rheumatology, Special Medical Center of China Air ForceHangzhou Aeronautical Sanatorium for Special Service of China Air ForceDepartment of Rheumatology, Jingjiang People’s HospitalHangzhou Aeronautical Sanatorium for Special Service of China Air ForceAbstract Background Obesity is a well-known modified risk factor for isolated systolic hypertension (ISH), but evidence is lacking regarding whether the combination of anthropometric and lipid indicators could strengthen their correlation with ISH. Therefore, we compared the association of body mass index (BMI), waist circumference (WC), waist-to-hip ratio (WHR), waist-to-height ratio (WHtR), visceral adiposity index (VAI), lipid accumulation product index (LAP), and cardiometabolic index (CMI) with ISH. Methods A total of 106,248 adults who received routine health screening and did not have diastolic blood pressure ≥ 90 mmHg were recruited in this cross-sectional study. The associations between these indicators and ISH were evaluated using multivariate regression. Results Each standard deviation (SD) increase in traditional obesity indicators (especially WHR and WHtR) had significantly higher multivariate-adjusted odds ratios (ORs) than each SD increase in lipid-related obesity indicators. In addition, multivariate-adjusted ORs for ISH in the third (vs. the first) tertile of traditional obesity indicators were also significantly higher than those of lipid-related indicators. Moreover, traditional obesity indicators exhibited a higher area under the ROC curve for discriminating ISH than lipid-related obesity indicators. Conclusions Traditional obesity indicators were more strongly associated with ISH than lipid-related obesity indicators among Chinese adults.https://doi.org/10.1186/s12872-022-02564-2HypertensionSystolic hypertensionAnthropometric indexObesity |
| spellingShingle | Jian Dong Qian Xiao Mei Li Dong Shui Chen Jian Qin Zhu Xing Zhen Liu Comparative analysis of the association between traditional and lipid-related obesity indicators and isolated systolic hypertension BMC Cardiovascular Disorders Hypertension Systolic hypertension Anthropometric index Obesity |
| title | Comparative analysis of the association between traditional and lipid-related obesity indicators and isolated systolic hypertension |
| title_full | Comparative analysis of the association between traditional and lipid-related obesity indicators and isolated systolic hypertension |
| title_fullStr | Comparative analysis of the association between traditional and lipid-related obesity indicators and isolated systolic hypertension |
| title_full_unstemmed | Comparative analysis of the association between traditional and lipid-related obesity indicators and isolated systolic hypertension |
| title_short | Comparative analysis of the association between traditional and lipid-related obesity indicators and isolated systolic hypertension |
| title_sort | comparative analysis of the association between traditional and lipid related obesity indicators and isolated systolic hypertension |
| topic | Hypertension Systolic hypertension Anthropometric index Obesity |
| url | https://doi.org/10.1186/s12872-022-02564-2 |
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