Novel antibacterial agent prepared by poly (hexamethylene guanidine hydrochloride) functionalized hollow nano-silica

A simple synthetic method of poly(hexamethylene guanidine hydrochloride) grafted hollow nano-silica (HSN-PHMG), a novel antibacterial material, was proposed. The water dispersibility and antibacterial property of HSN grafting of PHMG were improved. The hollow structure of nano-silica was characteriz...

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Bibliographic Details
Main Authors: ZHANG Zi-wen, ZHANG Kang-min, YANG Jian-jun, WU Qing-yun, WU Ming-yuan, ZHANG Jian-an, LIU Jiu-yi
Format: Article
Language:zho
Published: Journal of Materials Engineering 2019-03-01
Series:Cailiao gongcheng
Subjects:
Online Access:http://html.rhhz.net/CHXB/html/2020-3-40.htm
Description
Summary:A simple synthetic method of poly(hexamethylene guanidine hydrochloride) grafted hollow nano-silica (HSN-PHMG), a novel antibacterial material, was proposed. The water dispersibility and antibacterial property of HSN grafting of PHMG were improved. The hollow structure of nano-silica was characterized by scanning electron microscopy (SEM) and transmission electron microscopy (TEM). Fourier transform infrared spectroscopy (FTIR), X-ray photoelectron spectroscopy (XPS) and thermogravimetric analysis were used to characterize the successful grafting of PHMG and the mass fraction of PHMG is about 9.5% in HSN-PHMG. Antibacterial test using Escherichia coil (<i>E.coil</i>) and Staphylococcus aureus (<i>S.aureus</i>) as test strains and the results show that the minimum inhibitory concentration (MIC) of HSN-PHMG on <i>E.coil</i> and <i>S.aureus</i> are all 32 mg/L; <i>E.coil</i> can be completely killed within 2 h when the concentration of HSN-PHMG is 64 mg/L.
ISSN:1001-4381
1001-4381