Risk of hypertension in school-aged children with different parental risk: a longitudinal study from childhood to young adulthood
Abstract Background Although previous studies have shown the relationship between different parental factors and children’s blood pressure status, there is limited data on the cumulative effect of these factors. Considering parental socio-demographic, behavioral and cardio-metabolic characteristics,...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2021-08-01
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| Series: | BMC Pediatrics |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12887-021-02807-9 |
| _version_ | 1818600617495494656 |
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| author | Parisa Amiri Marjan Rezaei Sara Jalali-Farahani Mehrdad Karimi Leila Cheraghi Romina Esbati Fereidoun Azizi |
| author_facet | Parisa Amiri Marjan Rezaei Sara Jalali-Farahani Mehrdad Karimi Leila Cheraghi Romina Esbati Fereidoun Azizi |
| author_sort | Parisa Amiri |
| collection | DOAJ |
| description | Abstract Background Although previous studies have shown the relationship between different parental factors and children’s blood pressure status, there is limited data on the cumulative effect of these factors. Considering parental socio-demographic, behavioral and cardio-metabolic characteristics, the current study aimed to distinguish parental risk clusters and their impact on the incidence of hypertension in school-age children over 13 years. Methods Parental characteristics of 1669 children, including age, education, employment, smoking, physical activity, metabolic syndrome (MetS), hypertension (HTN), weight status, and diabetes were considered to categorize parents into low and high-risk clusters. Crude incidence rates (per 10,000 person-years) of HTN in children were assessed in each maternal and paternal cluster. Using Cox proportional hazard model, results on the association between parental risk clusters and HTN incidence in children were reported in five different models. Results Mean age of children was 13.96 ± 2.89 years, and 51.2% (n = 854) were girls. MetS, HTN, and weight status were the most important factors distinguishing low and high-risk parental clusters, respectively. Crude incidence rates (per 10,000 person-years) of HTN were 86 (95% CI: 71–106) and 38 (95% CI, 29–52) in boys and girls, respectively. Moreover, incidence rates (per 10,000 person-years) of HTN were 50 (95% CI, 40–63) and 80 (95% CI, 64–102) in maternal low and high-risk clusters, respectively. The incidence rates (per 10,000 person-years) of HTN in paternal low and high-risk clusters were 53 (95% CI, 41–70) and 68 (95% CI, 56–84), respectively. Conclusion Our findings underscore the prognostic value of maternal characteristics in predicting the incidence of HTN in their offspring. The current results could be valuable in planning related programs to prevent hypertension in similar communities. |
| first_indexed | 2024-12-16T12:38:20Z |
| format | Article |
| id | doaj.art-a38def36d7984c72bd5369666327e477 |
| institution | Directory Open Access Journal |
| issn | 1471-2431 |
| language | English |
| last_indexed | 2024-12-16T12:38:20Z |
| publishDate | 2021-08-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Pediatrics |
| spelling | doaj.art-a38def36d7984c72bd5369666327e4772022-12-21T22:31:29ZengBMCBMC Pediatrics1471-24312021-08-0121111110.1186/s12887-021-02807-9Risk of hypertension in school-aged children with different parental risk: a longitudinal study from childhood to young adulthoodParisa Amiri0Marjan Rezaei1Sara Jalali-Farahani2Mehrdad Karimi3Leila Cheraghi4Romina Esbati5Fereidoun Azizi6Research Center for Social Determinants of Health, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical SciencesResearch Center for Social Determinants of Health, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical SciencesResearch Center for Social Determinants of Health, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical SciencesResearch Center for Social Determinants of Health, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical SciencesResearch Center for Social Determinants of Health, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical SciencesResearch Center for Social Determinants of Health, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical SciencesEndocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical SciencesAbstract Background Although previous studies have shown the relationship between different parental factors and children’s blood pressure status, there is limited data on the cumulative effect of these factors. Considering parental socio-demographic, behavioral and cardio-metabolic characteristics, the current study aimed to distinguish parental risk clusters and their impact on the incidence of hypertension in school-age children over 13 years. Methods Parental characteristics of 1669 children, including age, education, employment, smoking, physical activity, metabolic syndrome (MetS), hypertension (HTN), weight status, and diabetes were considered to categorize parents into low and high-risk clusters. Crude incidence rates (per 10,000 person-years) of HTN in children were assessed in each maternal and paternal cluster. Using Cox proportional hazard model, results on the association between parental risk clusters and HTN incidence in children were reported in five different models. Results Mean age of children was 13.96 ± 2.89 years, and 51.2% (n = 854) were girls. MetS, HTN, and weight status were the most important factors distinguishing low and high-risk parental clusters, respectively. Crude incidence rates (per 10,000 person-years) of HTN were 86 (95% CI: 71–106) and 38 (95% CI, 29–52) in boys and girls, respectively. Moreover, incidence rates (per 10,000 person-years) of HTN were 50 (95% CI, 40–63) and 80 (95% CI, 64–102) in maternal low and high-risk clusters, respectively. The incidence rates (per 10,000 person-years) of HTN in paternal low and high-risk clusters were 53 (95% CI, 41–70) and 68 (95% CI, 56–84), respectively. Conclusion Our findings underscore the prognostic value of maternal characteristics in predicting the incidence of HTN in their offspring. The current results could be valuable in planning related programs to prevent hypertension in similar communities.https://doi.org/10.1186/s12887-021-02807-9HypertensionChildhoodParental risk |
| spellingShingle | Parisa Amiri Marjan Rezaei Sara Jalali-Farahani Mehrdad Karimi Leila Cheraghi Romina Esbati Fereidoun Azizi Risk of hypertension in school-aged children with different parental risk: a longitudinal study from childhood to young adulthood BMC Pediatrics Hypertension Childhood Parental risk |
| title | Risk of hypertension in school-aged children with different parental risk: a longitudinal study from childhood to young adulthood |
| title_full | Risk of hypertension in school-aged children with different parental risk: a longitudinal study from childhood to young adulthood |
| title_fullStr | Risk of hypertension in school-aged children with different parental risk: a longitudinal study from childhood to young adulthood |
| title_full_unstemmed | Risk of hypertension in school-aged children with different parental risk: a longitudinal study from childhood to young adulthood |
| title_short | Risk of hypertension in school-aged children with different parental risk: a longitudinal study from childhood to young adulthood |
| title_sort | risk of hypertension in school aged children with different parental risk a longitudinal study from childhood to young adulthood |
| topic | Hypertension Childhood Parental risk |
| url | https://doi.org/10.1186/s12887-021-02807-9 |
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