Targeting Cross-Presentation as a Route to Improve the Efficiency of Peptide-Based Cancer Vaccines

Targeting Cross-Presentation as a Route to Improve the Efficiency of Peptide-Based Cancer Vaccines

Cross-presenting dendritic cells (DC) offer an attractive target for vaccination due to their unique ability to process exogenous antigens for presentation on MHC class I molecules. Recent reports have established that these DC express unique surface receptors and play a critical role in the initiat...

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Bibliographic Details
Main Authors: Ben Wylie, Ferrer Ong, Hanane Belhoul-Fakir, Kristin Priebatsch, Heique Bogdawa, Anja Stirnweiss, Paul Watt, Paula Cunningham, Shane R. Stone, Jason Waithman
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cancers
Subjects:
peptide vaccine
cancer vaccine
dendritic cell
cell penetrating peptide
cross-presentation
melanoma
Online Access:https://www.mdpi.com/2072-6694/13/24/6189

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