Analysis of ovarian reserve markers (AMH, FSH, AFC) in different age strata in IVF/ICSI patients
Background: The predictive roles of follicle stimulating hormone (FSH), anti-mullerian hormone (AMH) and antral follicle count (AFC) as ovarian reserve markers in women with different age groups are not established well. Objective: This study compares the value of FSH, AMH and AFC at the time of in...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Shahid Sadoughi University of Medical Science, Yazd, Iran
2016-08-01
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| Series: | Iranian Journal of Reproductive Medicine |
| Online Access: | http://www.ssu.ac.ir/ijrm/index.php/ijrm/article/view/2037/1009 |
| _version_ | 1818229274342064128 |
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| author | Ensieh Shahrokh Tehraninezhad Fatemeh Mehrabi Raheleh Taati Vahid Kalantar Elham Aziminekoo Azam Tarafdari |
| author_facet | Ensieh Shahrokh Tehraninezhad Fatemeh Mehrabi Raheleh Taati Vahid Kalantar Elham Aziminekoo Azam Tarafdari |
| author_sort | Ensieh Shahrokh Tehraninezhad |
| collection | DOAJ |
| description | Background: The predictive roles of follicle stimulating hormone (FSH), anti-mullerian hormone (AMH) and antral follicle count (AFC) as ovarian reserve markers in women with different age groups are not established well.
Objective: This study compares the value of FSH, AMH and AFC at the time of in vitro fertilization (IVF) treatment in different age groups.
Materials and Methods: In this cross-sectional study, 103 women aged 20-43 years candidates for IVF/ICSI cycle were recruited. FSH, AMH and AFC on day 3 of menstrual cycle were measured. The relationship of these measured markers with outcome variables (oocytes number, number of frozen/fresh embryo and chemical and clinical pregnancy) was assessed in different age groups (i.e. 20-32, 33-37 and 38-43 years).
Results: our results show that age was correlated with clinical pregnancy, oocyte count and fresh and frozen embryo (p<0.001). AMH, AFC and FSH were not correlated with clinical or chemical pregnancy at total population or age subgroups except the significant correlation of AFC with clinical pregnancy at 33-37 years old group. AFC was correlated with oocyte count and the number of fresh and frozen embryos in the ages group 20-32 years. In this age group, AMH was correlated with fresh and frozen embryos. AMH, AFC and FSH were correlated with oocyte count and the number of fresh embryos in age group 33-37 years. AMH was correlated with oocyte count and the number of fresh embryos in 38-43 years old group.
Conclusion: We concluded that the age is the superior predictor of IVF outcome and AMH and AFC are variable predicting markers of ovarian reserve in different age groups. |
| first_indexed | 2024-12-12T10:16:00Z |
| format | Article |
| id | doaj.art-a392dc4e08f54b8aa72d7fbaf8ca0abf |
| institution | Directory Open Access Journal |
| issn | 1680-6433 2008-2177 |
| language | English |
| last_indexed | 2024-12-12T10:16:00Z |
| publishDate | 2016-08-01 |
| publisher | Shahid Sadoughi University of Medical Science, Yazd, Iran |
| record_format | Article |
| series | Iranian Journal of Reproductive Medicine |
| spelling | doaj.art-a392dc4e08f54b8aa72d7fbaf8ca0abf2022-12-22T00:27:40ZengShahid Sadoughi University of Medical Science, Yazd, IranIranian Journal of Reproductive Medicine1680-64332008-21772016-08-01148501506Analysis of ovarian reserve markers (AMH, FSH, AFC) in different age strata in IVF/ICSI patientsEnsieh Shahrokh Tehraninezhad0Fatemeh Mehrabi1Raheleh Taati2Vahid Kalantar3Elham Aziminekoo4Azam Tarafdari5Vali-e-Asr Reproductive Health Research Center, Department of Obstetrics and Gynecology, Imam Khomeini Complex Hospital, Tehran University of Medical Sciences, Tehran, Iran.Vali-e-Asr Reproductive Health Research Center, Department of Obstetrics and Gynecology, Imam Khomeini Complex Hospital, Tehran University of Medical Sciences, Tehran, Iran.Vali-e-Asr Reproductive Health Research Center, Department of Obstetrics and Gynecology, Imam Khomeini Complex Hospital, Tehran University of Medical Sciences, Tehran, Iran.Vali-e-Asr Reproductive Health Research Center, Department of Obstetrics and Gynecology, Imam Khomeini Complex Hospital, Tehran University of Medical Sciences, Tehran, Iran.Vali-e-Asr Reproductive Health Research Center, Department of Obstetrics and Gynecology, Imam Khomeini Complex Hospital, Tehran University of Medical Sciences, Tehran, Iran.Vali-e-Asr Reproductive Health Research Center, Department of Obstetrics and Gynecology, Imam Khomeini Complex Hospital, Tehran University of Medical Sciences, Tehran, Iran.Background: The predictive roles of follicle stimulating hormone (FSH), anti-mullerian hormone (AMH) and antral follicle count (AFC) as ovarian reserve markers in women with different age groups are not established well. Objective: This study compares the value of FSH, AMH and AFC at the time of in vitro fertilization (IVF) treatment in different age groups. Materials and Methods: In this cross-sectional study, 103 women aged 20-43 years candidates for IVF/ICSI cycle were recruited. FSH, AMH and AFC on day 3 of menstrual cycle were measured. The relationship of these measured markers with outcome variables (oocytes number, number of frozen/fresh embryo and chemical and clinical pregnancy) was assessed in different age groups (i.e. 20-32, 33-37 and 38-43 years). Results: our results show that age was correlated with clinical pregnancy, oocyte count and fresh and frozen embryo (p<0.001). AMH, AFC and FSH were not correlated with clinical or chemical pregnancy at total population or age subgroups except the significant correlation of AFC with clinical pregnancy at 33-37 years old group. AFC was correlated with oocyte count and the number of fresh and frozen embryos in the ages group 20-32 years. In this age group, AMH was correlated with fresh and frozen embryos. AMH, AFC and FSH were correlated with oocyte count and the number of fresh embryos in age group 33-37 years. AMH was correlated with oocyte count and the number of fresh embryos in 38-43 years old group. Conclusion: We concluded that the age is the superior predictor of IVF outcome and AMH and AFC are variable predicting markers of ovarian reserve in different age groups.http://www.ssu.ac.ir/ijrm/index.php/ijrm/article/view/2037/1009 |
| spellingShingle | Ensieh Shahrokh Tehraninezhad Fatemeh Mehrabi Raheleh Taati Vahid Kalantar Elham Aziminekoo Azam Tarafdari Analysis of ovarian reserve markers (AMH, FSH, AFC) in different age strata in IVF/ICSI patients Iranian Journal of Reproductive Medicine |
| title | Analysis of ovarian reserve markers (AMH, FSH, AFC) in different age strata in IVF/ICSI patients |
| title_full | Analysis of ovarian reserve markers (AMH, FSH, AFC) in different age strata in IVF/ICSI patients |
| title_fullStr | Analysis of ovarian reserve markers (AMH, FSH, AFC) in different age strata in IVF/ICSI patients |
| title_full_unstemmed | Analysis of ovarian reserve markers (AMH, FSH, AFC) in different age strata in IVF/ICSI patients |
| title_short | Analysis of ovarian reserve markers (AMH, FSH, AFC) in different age strata in IVF/ICSI patients |
| title_sort | analysis of ovarian reserve markers amh fsh afc in different age strata in ivf icsi patients |
| url | http://www.ssu.ac.ir/ijrm/index.php/ijrm/article/view/2037/1009 |
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