Study on the mechanism of efficient extracellular expression of toxic streptomyces phospholipase D in Brevibacillus choshinensis under Mg2+ stress

Study on the mechanism of efficient extracellular expression of toxic streptomyces phospholipase D in Brevibacillus choshinensis under Mg2+ stress

Abstract Background Phospholipase D (PLD) has significant advantages in the food and medicine industries due to its unique transphosphatidylation. However, the high heterologous expression of PLD is limited by its cytotoxicity. The present study sought to develop an efficient and extracellular expre...

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Bibliographic Details
Main Authors: Shaofeng Chen, Weide Xiong, Xurui Zhao, Weiyi Luo, Xuhui Yan, Yinghua Lu, Cuixue Chen, Xueping Ling
Format: Article
Language:English
Published: BMC 2022-03-01
Series:Microbial Cell Factories
Subjects:
Phospholipase D
Brevibacillus choshinensis
Magnesium stress
P2 promoter
Ion perturbation
Online Access:https://doi.org/10.1186/s12934-022-01770-z

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