Mineralization Content Alters Osteogenic Responses of Bone Marrow Stromal Cells on Hydroxyapatite/Polycaprolactone Composite Nanofiber Scaffolds

Mineralization Content Alters Osteogenic Responses of Bone Marrow Stromal Cells on Hydroxyapatite/Polycaprolactone Composite Nanofiber Scaffolds

Synthetic tissue scaffolds have a high potential impact for patients experiencing osteogenesis imperfecta. Using electrospinning, tissue scaffolds composed of hydroxyapatite/polycaprolactone (HAp/PCL) composite nanofibers were fabricated with two different HAp concentrations—1% and 10%...

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Bibliographic Details
Main Authors: Ketul C. Popat, Timothy T. Ruckh, Justin R. Weaver, Derek A. Carroll
Format: Article
Language:English
Published: MDPI AG 2012-11-01
Series:Journal of Functional Biomaterials
Subjects:
nanofiber
scaffold
bone
hydroxyapatite
gene expression
Online Access:http://www.mdpi.com/2079-4983/3/4/776

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