Impact of a Primary Care Antimicrobial Stewardship Program on Bacterial Resistance Control and Ecological Imprint in Urinary Tract Infections
Antimicrobial stewardship programs (ASPs) are a central component in reducing the overprescription of unnecessary antibiotics, with multiple studies showing benefits in the reduction of bacterial resistance. Less commonly, ASPs have been performed in outpatient settings, but there is a lack of avail...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-12-01
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| Series: | Antibiotics |
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| Online Access: | https://www.mdpi.com/2079-6382/11/12/1776 |
| _version_ | 1797461782235709440 |
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| author | Alfredo Jover-Sáenz María Ramírez-Hidalgo Alba Bellés Bellés Esther Ribes Murillo Meritxell Batlle Bosch José Cayado Cabanillas Sònia Garrido-Calvo María Isabel Gracia Vilas Laura Gros Navés María Jesús Javierre Caudevilla Alba Mari López Lidia Montull Navarro Mireia Ortiz Valls Gemma Terrer Manrique Pilar Vaqué Castilla José Javier Ichart Tomás Elena Justribó Sánchez Ester Andreu Mayor Joan Carrera Guiu Roser Martorell Solé Silvia Pallàs Satué Mireia Saura Codina Ana Vena Martínez José Manuel Albalat Samper Susana Cano Marrón Isabel Chacón Domínguez David de la Rica Escuin María José Estadella Servalls Ana M. Figueres Farreny Sonia Minguet Vidal Luís Miguel Montaña Esteban Josep Otal Bareche Mercè Pallerola Planes Francesc Pujol Aymerich Andrés Rodríguez Garrocho Antoni Solé Curcó Francisca Toribio Redondo María Cruz Urgelés Castillón Juan Valgañon Palacios Joan Torres-Puig-gros the P-ILEHRDA Group on behalf of Translational Research Group on Infectious Diseases of Lleida (Head Group, TRIDLE-IRBLleida) |
| author_facet | Alfredo Jover-Sáenz María Ramírez-Hidalgo Alba Bellés Bellés Esther Ribes Murillo Meritxell Batlle Bosch José Cayado Cabanillas Sònia Garrido-Calvo María Isabel Gracia Vilas Laura Gros Navés María Jesús Javierre Caudevilla Alba Mari López Lidia Montull Navarro Mireia Ortiz Valls Gemma Terrer Manrique Pilar Vaqué Castilla José Javier Ichart Tomás Elena Justribó Sánchez Ester Andreu Mayor Joan Carrera Guiu Roser Martorell Solé Silvia Pallàs Satué Mireia Saura Codina Ana Vena Martínez José Manuel Albalat Samper Susana Cano Marrón Isabel Chacón Domínguez David de la Rica Escuin María José Estadella Servalls Ana M. Figueres Farreny Sonia Minguet Vidal Luís Miguel Montaña Esteban Josep Otal Bareche Mercè Pallerola Planes Francesc Pujol Aymerich Andrés Rodríguez Garrocho Antoni Solé Curcó Francisca Toribio Redondo María Cruz Urgelés Castillón Juan Valgañon Palacios Joan Torres-Puig-gros the P-ILEHRDA Group on behalf of Translational Research Group on Infectious Diseases of Lleida (Head Group, TRIDLE-IRBLleida) |
| author_sort | Alfredo Jover-Sáenz |
| collection | DOAJ |
| description | Antimicrobial stewardship programs (ASPs) are a central component in reducing the overprescription of unnecessary antibiotics, with multiple studies showing benefits in the reduction of bacterial resistance. Less commonly, ASPs have been performed in outpatient settings, but there is a lack of available data in these settings. We implemented an ASP in a large regional outpatient setting to assess its feasibility and effectiveness. Over a 5-year post-implementation period, compared to the pre-intervention period, a significant reduction in antibiotic prescription occurred, with a reduction in resistance in <i>E. coli</i> urinary isolates. ASP activities also were found to be cost-effective, with a reduction in medication prescription. |
| first_indexed | 2024-03-09T17:24:14Z |
| format | Article |
| id | doaj.art-a3938b0b88d943169086d6fe76a1069c |
| institution | Directory Open Access Journal |
| issn | 2079-6382 |
| language | English |
| last_indexed | 2024-03-09T17:24:14Z |
| publishDate | 2022-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antibiotics |
| spelling | doaj.art-a3938b0b88d943169086d6fe76a1069c2023-11-24T12:54:12ZengMDPI AGAntibiotics2079-63822022-12-011112177610.3390/antibiotics11121776Impact of a Primary Care Antimicrobial Stewardship Program on Bacterial Resistance Control and Ecological Imprint in Urinary Tract InfectionsAlfredo Jover-Sáenz0María Ramírez-Hidalgo1Alba Bellés Bellés2Esther Ribes Murillo3Meritxell Batlle Bosch4José Cayado Cabanillas5Sònia Garrido-Calvo6María Isabel Gracia Vilas7Laura Gros Navés8María Jesús Javierre Caudevilla9Alba Mari López10Lidia Montull Navarro11Mireia Ortiz Valls12Gemma Terrer Manrique13Pilar Vaqué Castilla14José Javier Ichart Tomás15Elena Justribó Sánchez16Ester Andreu Mayor17Joan Carrera Guiu18Roser Martorell Solé19Silvia Pallàs Satué20Mireia Saura Codina21Ana Vena Martínez22José Manuel Albalat Samper23Susana Cano Marrón24Isabel Chacón Domínguez25David de la Rica Escuin26María José Estadella Servalls27Ana M. Figueres Farreny28Sonia Minguet Vidal29Luís Miguel Montaña Esteban30Josep Otal Bareche31Mercè Pallerola Planes32Francesc Pujol Aymerich33Andrés Rodríguez Garrocho34Antoni Solé Curcó35Francisca Toribio Redondo36María Cruz Urgelés Castillón37Juan Valgañon Palacios38Joan Torres-Puig-gros39the P-ILEHRDA Groupon behalf of Translational Research Group on Infectious Diseases of Lleida (Head Group, TRIDLE-IRBLleida)Unidad Territorial Infección Nosocomial (UTIN), Hospital Universitari Arnau de Vilanova de Lleida (HUAV), Institut de Recerca Biomèdica (IRBLleida), 25198 Lleida, SpainUnidad Territorial Infección Nosocomial (UTIN), Hospital Universitari Arnau de Vilanova de Lleida (HUAV), Institut de Recerca Biomèdica (IRBLleida), 25198 Lleida, SpainSección de Microbiología, HUAV, 25198 Lleida, SpainUnidad de Farmacia de Atención Primaria, Institut Català de la Salut (ICS), 25007 Lleida, SpainEquipo de Atención Priamaria (EAP) Les Borges Blanques, 25400 Lleida, SpainEAP Pla d’Urgell, 25001 Lleida, SpainEAP Balàfia-Pardinyes, 25005 Lleida, SpainEAP Rambla de Ferran, 25007 Lleida, SpainEAP Lleida Rural Nord, 25110 Lleida, SpainCentre Penitenciari de Ponent, 25199 Lleida, SpainEAP Pla d’Urgell, 25001 Lleida, SpainEAP Eixample, 25006 Lleida, SpainEAP Balàfia-Pardinyes, 25005 Lleida, SpainEAP Balàfia-Pardinyes, 25005 Lleida, SpainEAP Primer de Maig, 25002 Lleida, SpainServicio de Urgencias. HUAV, 25198 Lleida, SpainCentre Urgències Atenció Primària (CUAP), 25004 Lleida, SpainCol·legi Oficial de Podòlegs, 25001 Lleida, SpainCol·legi Oficial de Odontòlegs, 25002 Lleida, SpainEAP Cervera,25200 Lleida, SpainCol·legi Farmacèutics de Lleida, 25007 Lleida, SpainServicio de Urgencias. HUAV, 25198 Lleida, SpainServei de Geriatria, Hospital Universitari Santa Maria, 25198 Lleida, SpainEAP Ponts, 25740 Lleida, SpainEAP Onze de Setembre, 25005 Lleida, SpainEAP Bellpuig, 25250 Lleida, SpainEAP Artesa de Segre, 25730 Lleida, SpainEAP Cappont, 25001 Lleida, SpainEAP Almacelles, 25100 Lleida, SpainEAP Agramunt, 25310 Lleida, SpainEAP Seròs, 25183 Lleida, SpainEAP Lleida Rural Sud, 25171 Lleida, SpainEAP Balaguer, 25600 Lleida, SpainEAP Alcarràs, 25180 Lleida, SpainEAP Tàrrega, 25300 Lleida, SpainEAP Cervera,25200 Lleida, SpainEAP Alfarràs-Almenar, 25120 Lleida, SpainEAP Bordeta—Magraners, 25001 Lleida, SpainEAP La Granadella, 25177 Lleida, SpainDepartament de Salut Pública, Universitat de Lleida (UdL), 25006 Lleida, SpainAntimicrobial stewardship programs (ASPs) are a central component in reducing the overprescription of unnecessary antibiotics, with multiple studies showing benefits in the reduction of bacterial resistance. Less commonly, ASPs have been performed in outpatient settings, but there is a lack of available data in these settings. We implemented an ASP in a large regional outpatient setting to assess its feasibility and effectiveness. Over a 5-year post-implementation period, compared to the pre-intervention period, a significant reduction in antibiotic prescription occurred, with a reduction in resistance in <i>E. coli</i> urinary isolates. ASP activities also were found to be cost-effective, with a reduction in medication prescription.https://www.mdpi.com/2079-6382/11/12/1776antimicrobial stewardshipuse antimicrobialsmultidrug-resistant microorganismscommunity onsetepidemiology |
| spellingShingle | Alfredo Jover-Sáenz María Ramírez-Hidalgo Alba Bellés Bellés Esther Ribes Murillo Meritxell Batlle Bosch José Cayado Cabanillas Sònia Garrido-Calvo María Isabel Gracia Vilas Laura Gros Navés María Jesús Javierre Caudevilla Alba Mari López Lidia Montull Navarro Mireia Ortiz Valls Gemma Terrer Manrique Pilar Vaqué Castilla José Javier Ichart Tomás Elena Justribó Sánchez Ester Andreu Mayor Joan Carrera Guiu Roser Martorell Solé Silvia Pallàs Satué Mireia Saura Codina Ana Vena Martínez José Manuel Albalat Samper Susana Cano Marrón Isabel Chacón Domínguez David de la Rica Escuin María José Estadella Servalls Ana M. Figueres Farreny Sonia Minguet Vidal Luís Miguel Montaña Esteban Josep Otal Bareche Mercè Pallerola Planes Francesc Pujol Aymerich Andrés Rodríguez Garrocho Antoni Solé Curcó Francisca Toribio Redondo María Cruz Urgelés Castillón Juan Valgañon Palacios Joan Torres-Puig-gros the P-ILEHRDA Group on behalf of Translational Research Group on Infectious Diseases of Lleida (Head Group, TRIDLE-IRBLleida) Impact of a Primary Care Antimicrobial Stewardship Program on Bacterial Resistance Control and Ecological Imprint in Urinary Tract Infections Antibiotics antimicrobial stewardship use antimicrobials multidrug-resistant microorganisms community onset epidemiology |
| title | Impact of a Primary Care Antimicrobial Stewardship Program on Bacterial Resistance Control and Ecological Imprint in Urinary Tract Infections |
| title_full | Impact of a Primary Care Antimicrobial Stewardship Program on Bacterial Resistance Control and Ecological Imprint in Urinary Tract Infections |
| title_fullStr | Impact of a Primary Care Antimicrobial Stewardship Program on Bacterial Resistance Control and Ecological Imprint in Urinary Tract Infections |
| title_full_unstemmed | Impact of a Primary Care Antimicrobial Stewardship Program on Bacterial Resistance Control and Ecological Imprint in Urinary Tract Infections |
| title_short | Impact of a Primary Care Antimicrobial Stewardship Program on Bacterial Resistance Control and Ecological Imprint in Urinary Tract Infections |
| title_sort | impact of a primary care antimicrobial stewardship program on bacterial resistance control and ecological imprint in urinary tract infections |
| topic | antimicrobial stewardship use antimicrobials multidrug-resistant microorganisms community onset epidemiology |
| url | https://www.mdpi.com/2079-6382/11/12/1776 |
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