Point-of-Care Technologies for the Advancement of Precision Medicine in Heart, Lung, Blood, and Sleep Disorders

The commercialization of new point of care technologies holds great potential in facilitating and advancing precision medicine in heart, lung, blood, and sleep (HLBS) disorders. The delivery of individually tailored health care to a patient depends on how well that patient's health condition ca...

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Main Authors: Mary Emma Gorham Bigelow, Brian G. Jamieson, Chi On Chui, Yufei Mao, Kyeong-Sik Shin, Tony Jun Huang, Po-Hsun Huang, Liqiang Ren, Bishow Adhikari, Jue Chen, Erin Iturriaga
Format: Article
Language:English
Published: IEEE 2016-01-01
Series:IEEE Journal of Translational Engineering in Health and Medicine
Subjects:
Online Access:https://ieeexplore.ieee.org/document/7518992/
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author Mary Emma Gorham Bigelow
Brian G. Jamieson
Chi On Chui
Yufei Mao
Kyeong-Sik Shin
Tony Jun Huang
Po-Hsun Huang
Liqiang Ren
Bishow Adhikari
Jue Chen
Erin Iturriaga
author_facet Mary Emma Gorham Bigelow
Brian G. Jamieson
Chi On Chui
Yufei Mao
Kyeong-Sik Shin
Tony Jun Huang
Po-Hsun Huang
Liqiang Ren
Bishow Adhikari
Jue Chen
Erin Iturriaga
author_sort Mary Emma Gorham Bigelow
collection DOAJ
description The commercialization of new point of care technologies holds great potential in facilitating and advancing precision medicine in heart, lung, blood, and sleep (HLBS) disorders. The delivery of individually tailored health care to a patient depends on how well that patient's health condition can be interrogated and monitored. Point of care technologies may enable access to rapid and cost-effective interrogation of a patient's health condition in near real time. Currently, physiological data are largely limited to single-time-point collection at the hospital or clinic, whereas critical information on some conditions must be collected in the home, when symptoms occur, or at regular intervals over time. A variety of HLBS disorders are highly dependent on transient variables, such as patient activity level, environment, time of day, and so on. Consequently, the National Heart Lung and Blood Institute sponsored a request for applications to support the development and commercialization of novel point-of-care technologies through small businesses (RFA-HL-14-011 and RFA-HL-14-017). Three of the supported research projects are described to highlight particular point-of-care needs for HLBS disorders and the breadth of emerging technologies. While significant obstacles remain to the commercialization of such technologies, these advancements will be required to achieve precision medicine.
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spelling doaj.art-a3963f84f20e4774ad94ffd2bdef50452022-12-21T23:44:21ZengIEEEIEEE Journal of Translational Engineering in Health and Medicine2168-23722016-01-01411010.1109/JTEHM.2016.25939207518992Point-of-Care Technologies for the Advancement of Precision Medicine in Heart, Lung, Blood, and Sleep DisordersMary Emma Gorham Bigelow0https://orcid.org/0000-0003-4334-3735Brian G. Jamieson1Chi On Chui2Yufei Mao3Kyeong-Sik Shin4Tony Jun Huang5Po-Hsun Huang6Liqiang Ren7Bishow Adhikari8Jue Chen9Erin Iturriaga10Diagnostic Biochips, Inc., Glen Burnie, MD, USADiagnostic Biochips, Inc., Glen Burnie, MD, USAElectrical Engineering and Bioengineering Departments, University of California at Los Angeles, Los Angeles, CA, USAElectrical Engineering and Bioengineering Departments, University of California at Los Angeles, Los Angeles, CA, USAElectrical Engineering and Bioengineering Departments, University of California at Los Angeles, Los Angeles, CA, USABioengineering Science and Mechanics Department, The Pennsylvania State University, University Park, PA, USABioengineering Science and Mechanics Department, The Pennsylvania State University, University Park, PA, USABioengineering Science and Mechanics Department, The Pennsylvania State University, University Park, PA, USANational Heart, Lung, and Blood Institute, Bethesda, MD, USANational Heart, Lung, and Blood Institute, Bethesda, MD, USANational Heart, Lung, and Blood Institute, Bethesda, MD, USAThe commercialization of new point of care technologies holds great potential in facilitating and advancing precision medicine in heart, lung, blood, and sleep (HLBS) disorders. The delivery of individually tailored health care to a patient depends on how well that patient's health condition can be interrogated and monitored. Point of care technologies may enable access to rapid and cost-effective interrogation of a patient's health condition in near real time. Currently, physiological data are largely limited to single-time-point collection at the hospital or clinic, whereas critical information on some conditions must be collected in the home, when symptoms occur, or at regular intervals over time. A variety of HLBS disorders are highly dependent on transient variables, such as patient activity level, environment, time of day, and so on. Consequently, the National Heart Lung and Blood Institute sponsored a request for applications to support the development and commercialization of novel point-of-care technologies through small businesses (RFA-HL-14-011 and RFA-HL-14-017). Three of the supported research projects are described to highlight particular point-of-care needs for HLBS disorders and the breadth of emerging technologies. While significant obstacles remain to the commercialization of such technologies, these advancements will be required to achieve precision medicine.https://ieeexplore.ieee.org/document/7518992/Biosensorcommercializationpoint-of-care technologiesprecision medicine
spellingShingle Mary Emma Gorham Bigelow
Brian G. Jamieson
Chi On Chui
Yufei Mao
Kyeong-Sik Shin
Tony Jun Huang
Po-Hsun Huang
Liqiang Ren
Bishow Adhikari
Jue Chen
Erin Iturriaga
Point-of-Care Technologies for the Advancement of Precision Medicine in Heart, Lung, Blood, and Sleep Disorders
IEEE Journal of Translational Engineering in Health and Medicine
Biosensor
commercialization
point-of-care technologies
precision medicine
title Point-of-Care Technologies for the Advancement of Precision Medicine in Heart, Lung, Blood, and Sleep Disorders
title_full Point-of-Care Technologies for the Advancement of Precision Medicine in Heart, Lung, Blood, and Sleep Disorders
title_fullStr Point-of-Care Technologies for the Advancement of Precision Medicine in Heart, Lung, Blood, and Sleep Disorders
title_full_unstemmed Point-of-Care Technologies for the Advancement of Precision Medicine in Heart, Lung, Blood, and Sleep Disorders
title_short Point-of-Care Technologies for the Advancement of Precision Medicine in Heart, Lung, Blood, and Sleep Disorders
title_sort point of care technologies for the advancement of precision medicine in heart lung blood and sleep disorders
topic Biosensor
commercialization
point-of-care technologies
precision medicine
url https://ieeexplore.ieee.org/document/7518992/
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