Polycomb group proteins bind an engrailed PRE in both the "ON" and "OFF" transcriptional states of engrailed.

Polycomb group proteins bind an engrailed PRE in both the "ON" and "OFF" transcriptional states of engrailed.

Polycomb group (PcG) and trithorax Group (trxG) proteins maintain the "OFF" and "ON" transcriptional states of HOX genes and other targets by modulation of chromatin structure. In Drosophila, PcG proteins are bound to DNA fragments called Polycomb group response elements (PREs)....

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Bibliographic Details
Main Authors: Kristofor K Langlais, J Lesley Brown, Judith A Kassis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3490902?pdf=render

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