Data supporting the physico-chemical characterization, cellular uptake and cytotoxicity of lipid nanocapsules

The aim of this data article is to provide data for a basic knowledge of the properties of lipid nanocapsules, a new colloidal system with very promising applications in drug delivery. Firstly, we pay attention on how it is possible to determine their surface composition by means of electrokinetics...

Full description

Bibliographic Details
Main Authors: P. Sánchez-Moreno, J.L. Ortega-Vinuesa, H. Boulaiz, J.A. Marchal, J.M. Peula-García
Format: Article
Language:English
Published: Elsevier 2015-09-01
Series:Data in Brief
Online Access:http://www.sciencedirect.com/science/article/pii/S2352340915000943
_version_ 1819050912896778240
author P. Sánchez-Moreno
J.L. Ortega-Vinuesa
H. Boulaiz
J.A. Marchal
J.M. Peula-García
author_facet P. Sánchez-Moreno
J.L. Ortega-Vinuesa
H. Boulaiz
J.A. Marchal
J.M. Peula-García
author_sort P. Sánchez-Moreno
collection DOAJ
description The aim of this data article is to provide data for a basic knowledge of the properties of lipid nanocapsules, a new colloidal system with very promising applications in drug delivery. Firstly, we pay attention on how it is possible to determine their surface composition by means of electrokinetics measurements. On the other hand, we provide experimental evidences for a better understanding of the factors that determine the interactions of these nanoparticles with cells as a necessary step to guide the design of the most effective formulations. Additionally, we supply information about encapsulation efficiency of docetaxel, a potent chemotherapy drug, inside nanocapsules supporting the experimental cytotoxicity results of these nanosystems.
first_indexed 2024-12-21T11:55:35Z
format Article
id doaj.art-a39dbe59cb654fcfbff36bd5bf10c797
institution Directory Open Access Journal
issn 2352-3409
language English
last_indexed 2024-12-21T11:55:35Z
publishDate 2015-09-01
publisher Elsevier
record_format Article
series Data in Brief
spelling doaj.art-a39dbe59cb654fcfbff36bd5bf10c7972022-12-21T19:04:57ZengElsevierData in Brief2352-34092015-09-014C27928410.1016/j.dib.2015.06.002Data supporting the physico-chemical characterization, cellular uptake and cytotoxicity of lipid nanocapsulesP. Sánchez-Moreno0J.L. Ortega-Vinuesa1H. Boulaiz2J.A. Marchal3J.M. Peula-García4European Center for Nanomedicine (CEN), Laboratory of Nanostructured Fluorinated Materials (NFMLab), Department of Chemistry, Materials, and Chemical Engineering “Giulio Natta”, Politecnico di Milano, 20131 ItalyBiocolloid and Fluid Physics Group, Department of Applied Physics, University of Granada, 18071 Granada, SpainBiopathology and Regenerative Medicine Institute (IBIMER), Centre for Biomedical Research, University of Granada, Granada E-18100, SpainBiopathology and Regenerative Medicine Institute (IBIMER), Centre for Biomedical Research, University of Granada, Granada E-18100, SpainBiocolloid and Fluid Physics Group, Department of Applied Physics, University of Granada, 18071 Granada, SpainThe aim of this data article is to provide data for a basic knowledge of the properties of lipid nanocapsules, a new colloidal system with very promising applications in drug delivery. Firstly, we pay attention on how it is possible to determine their surface composition by means of electrokinetics measurements. On the other hand, we provide experimental evidences for a better understanding of the factors that determine the interactions of these nanoparticles with cells as a necessary step to guide the design of the most effective formulations. Additionally, we supply information about encapsulation efficiency of docetaxel, a potent chemotherapy drug, inside nanocapsules supporting the experimental cytotoxicity results of these nanosystems.http://www.sciencedirect.com/science/article/pii/S2352340915000943
spellingShingle P. Sánchez-Moreno
J.L. Ortega-Vinuesa
H. Boulaiz
J.A. Marchal
J.M. Peula-García
Data supporting the physico-chemical characterization, cellular uptake and cytotoxicity of lipid nanocapsules
Data in Brief
title Data supporting the physico-chemical characterization, cellular uptake and cytotoxicity of lipid nanocapsules
title_full Data supporting the physico-chemical characterization, cellular uptake and cytotoxicity of lipid nanocapsules
title_fullStr Data supporting the physico-chemical characterization, cellular uptake and cytotoxicity of lipid nanocapsules
title_full_unstemmed Data supporting the physico-chemical characterization, cellular uptake and cytotoxicity of lipid nanocapsules
title_short Data supporting the physico-chemical characterization, cellular uptake and cytotoxicity of lipid nanocapsules
title_sort data supporting the physico chemical characterization cellular uptake and cytotoxicity of lipid nanocapsules
url http://www.sciencedirect.com/science/article/pii/S2352340915000943
work_keys_str_mv AT psanchezmoreno datasupportingthephysicochemicalcharacterizationcellularuptakeandcytotoxicityoflipidnanocapsules
AT jlortegavinuesa datasupportingthephysicochemicalcharacterizationcellularuptakeandcytotoxicityoflipidnanocapsules
AT hboulaiz datasupportingthephysicochemicalcharacterizationcellularuptakeandcytotoxicityoflipidnanocapsules
AT jamarchal datasupportingthephysicochemicalcharacterizationcellularuptakeandcytotoxicityoflipidnanocapsules
AT jmpeulagarcia datasupportingthephysicochemicalcharacterizationcellularuptakeandcytotoxicityoflipidnanocapsules