Staphylococcus aureus pathogenicity Factors and their Role in the Infection process and the induction of the postvaccination immunity
The rapid development of molecular-biological and genetic methods of research led to the broadening and deepening of knowledge of the pathogenesis of infection diseases, the structure of pathogenicity factors and their role in the development of the post-infection and post-vaccination immunity. In t...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
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Numikom LLC
2016-06-01
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| Series: | Эпидемиология и вакцинопрофилактика |
| Subjects: | |
| Online Access: | https://www.epidemvac.ru/jour/article/view/168 |
| _version_ | 1826567547992932352 |
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| author | I. M. Gruber N. B. Egorova E. A. Astashkina |
| author_facet | I. M. Gruber N. B. Egorova E. A. Astashkina |
| author_sort | I. M. Gruber |
| collection | DOAJ |
| description | The rapid development of molecular-biological and genetic methods of research led to the broadening and deepening of knowledge of the pathogenesis of infection diseases, the structure of pathogenicity factors and their role in the development of the post-infection and post-vaccination immunity. In the review presented the literature data of this problem in relation to diseases, caused by S. aureus, which acquired great social and economic significance. Presented the list of numerous pathogenicity factors of S. aureus, their significance in the development of the infectious process and the results used to create vaccine preparations. Most of the vaccines in the construction of which used the capsular polysaccharides, toxins, protein antigens of the cell wall are in various stages of preclinical and clinical trials. Preliminary data indicate a need to use it to create protective immunity multiantigenic complex with focus on numerous factors of pathogenicity of S. aureus. |
| first_indexed | 2024-04-10T02:51:17Z |
| format | Article |
| id | doaj.art-a39fb69954ac44ba9d56c9e59e219ac5 |
| institution | Directory Open Access Journal |
| issn | 2073-3046 2619-0494 |
| language | Russian |
| last_indexed | 2025-03-14T11:09:17Z |
| publishDate | 2016-06-01 |
| publisher | Numikom LLC |
| record_format | Article |
| series | Эпидемиология и вакцинопрофилактика |
| spelling | doaj.art-a39fb69954ac44ba9d56c9e59e219ac52025-03-02T10:40:26ZrusNumikom LLCЭпидемиология и вакцинопрофилактика2073-30462619-04942016-06-01153728210.31631/2073-3046-2016-15-3-72-82167Staphylococcus aureus pathogenicity Factors and their Role in the Infection process and the induction of the postvaccination immunityI. M. Gruber0N. B. Egorova1E. A. Astashkina2Federal State Budgetary Research Institution «I.I. Mechnikov Sientific Research Institute for Vaccine and Sera»Federal State Budgetary Research Institution «I.I. Mechnikov Sientific Research Institute for Vaccine and Sera»Federal State Budgetary Research Institution «I.I. Mechnikov Sientific Research Institute for Vaccine and Sera»The rapid development of molecular-biological and genetic methods of research led to the broadening and deepening of knowledge of the pathogenesis of infection diseases, the structure of pathogenicity factors and their role in the development of the post-infection and post-vaccination immunity. In the review presented the literature data of this problem in relation to diseases, caused by S. aureus, which acquired great social and economic significance. Presented the list of numerous pathogenicity factors of S. aureus, their significance in the development of the infectious process and the results used to create vaccine preparations. Most of the vaccines in the construction of which used the capsular polysaccharides, toxins, protein antigens of the cell wall are in various stages of preclinical and clinical trials. Preliminary data indicate a need to use it to create protective immunity multiantigenic complex with focus on numerous factors of pathogenicity of S. aureus.https://www.epidemvac.ru/jour/article/view/168staphylococcus aureusфакторы патогенностикапсульный полисахаридтоксинвакцинаинфекционный процесспоствакцинальный иммунитетэкспериментальные моделиstaphylococcus aureuspathogenicity factorscapsular polysaccharidetoxinvaccineinfection processpost-vaccination immunityexperimental models |
| spellingShingle | I. M. Gruber N. B. Egorova E. A. Astashkina Staphylococcus aureus pathogenicity Factors and their Role in the Infection process and the induction of the postvaccination immunity Эпидемиология и вакцинопрофилактика staphylococcus aureus факторы патогенности капсульный полисахарид токсин вакцина инфекционный процесс поствакцинальный иммунитет экспериментальные модели staphylococcus aureus pathogenicity factors capsular polysaccharide toxin vaccine infection process post-vaccination immunity experimental models |
| title | Staphylococcus aureus pathogenicity Factors and their Role in the Infection process and the induction of the postvaccination immunity |
| title_full | Staphylococcus aureus pathogenicity Factors and their Role in the Infection process and the induction of the postvaccination immunity |
| title_fullStr | Staphylococcus aureus pathogenicity Factors and their Role in the Infection process and the induction of the postvaccination immunity |
| title_full_unstemmed | Staphylococcus aureus pathogenicity Factors and their Role in the Infection process and the induction of the postvaccination immunity |
| title_short | Staphylococcus aureus pathogenicity Factors and their Role in the Infection process and the induction of the postvaccination immunity |
| title_sort | staphylococcus aureus pathogenicity factors and their role in the infection process and the induction of the postvaccination immunity |
| topic | staphylococcus aureus факторы патогенности капсульный полисахарид токсин вакцина инфекционный процесс поствакцинальный иммунитет экспериментальные модели staphylococcus aureus pathogenicity factors capsular polysaccharide toxin vaccine infection process post-vaccination immunity experimental models |
| url | https://www.epidemvac.ru/jour/article/view/168 |
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