Cardiolipin Synthesis and Outer Membrane Localization Are Required for <italic toggle="yes">Shigella flexneri</italic> Virulence

Cardiolipin Synthesis and Outer Membrane Localization Are Required for <italic toggle="yes">Shigella flexneri</italic> Virulence

ABSTRACT Cardiolipin, an anionic phospholipid that resides at the poles of the inner and outer membranes, is synthesized primarily by the putative cardiolipin synthase ClsA in Shigella flexneri. An S. flexneri clsA mutant had no cardiolipin detected within its membrane, grew normally in vitro, and i...

Full description

Bibliographic Details
Main Authors: Rachael M. Rossi, Lauren Yum, Hervé Agaisse, Shelley M. Payne
Format: Article
Language:English
Published: American Society for Microbiology 2017-09-01
Series:mBio
Subjects:
IcsA
Shigella flexneri
cardiolipin
cell-cell spread
outer membrane
Online Access:https://journals.asm.org/doi/10.1128/mBio.01199-17

Similar Items

Similar Items