Modulation of RECK levels in Xenopus A6 cells: effects on MT1-MMP, MMP-2 and pERK levels
Abstract Background MT1-MMP is a cell-surface enzyme whose regulation of pro-MMP-2 and ERK activation position it as a key facilitator of ECM remodelling and cell migration. These processes are modulated by endogenous MMP inhibitors, such as RECK, a GPI-anchored protein which has been shown to inhib...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Aristotle University of Thessaloniki
2019-11-01
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| Series: | Journal of Biological Research - Thessaloniki |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s40709-019-0108-8 |