Toxoplasmosis in Relation to Entameba Histolytica and Giardia Lamblia Infection
This study was carried out in Baghdad , on 150 individuals (82 females, 68 males ) , were divided into four groups on the bases of parasitological and serological findings : group I : Control healthy Individuals : negative for toxoplasmosis and E . histolytica and G. lamblia ( 20, 13.3% )grou...
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| Format: | Article |
| Language: | English |
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College of medicine/ University of Diyala
2019-11-01
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| Series: | Diyala Journal of Medicine |
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| Online Access: | http://djm.uodiyala.edu.iq/index.php/djm/article/view/445 |
| Summary: | This study was carried out in Baghdad , on 150 individuals (82 females, 68 males ) , were divided into four groups on the bases of parasitological and serological findings : group I : Control healthy Individuals : negative for toxoplasmosis and E . histolytica and G. lamblia ( 20, 13.3% )group II : positive for toxoplasmosis alone (30 , 20%), group III: positive forE histolytica ,and G. lamblia (63 , 42%), group IV: positive for toxoplasmosis , E . histolytica and G . lamblia ( Mixed infection 37 , 24.7% ).
The results of this study showed highly significant increase in serum levels of interleukin
-12 ( IL- 12 ) in all groups especially in group IV , followed by group II .The serum level
of Interferon –gamma ( IFN- g ) showed also significant increase(P <0.05)in group IV, followed by group III , but nonsignificant (P >0.05) in group II .
There was also significant increase in serum concentration of IgG , IgM,and IgE in group
IV , but nonsignificant level was recorded in IgE of group II .
When comparing group II with the group IV , there was significant difference in serum
levels of IL-12 , IFN-g , IgG , IgM and IgE .
It was concluded that mixed infection with these parasites could provide a strong synergestic
action to induce both cell mediated and humoral immunity .
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| ISSN: | 2219-9764 2617-8982 |