Bridging gaps in transposable element research with single-molecule and single-cell technologies
Abstract More than half of the genomic landscape in humans and many other organisms is composed of repetitive DNA, which mostly derives from transposable elements (TEs) and viruses. Recent technological advances permit improved assessment of the repetitive content across genomes and newly developed...
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| Format: | Article |
| Language: | English |
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BMC
2018-12-01
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| Series: | Mobile DNA |
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| Online Access: | http://link.springer.com/article/10.1186/s13100-018-0140-5 |
| _version_ | 1818381342962876416 |
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| author | Claudia Kutter Patric Jern Alexander Suh |
| author_facet | Claudia Kutter Patric Jern Alexander Suh |
| author_sort | Claudia Kutter |
| collection | DOAJ |
| description | Abstract More than half of the genomic landscape in humans and many other organisms is composed of repetitive DNA, which mostly derives from transposable elements (TEs) and viruses. Recent technological advances permit improved assessment of the repetitive content across genomes and newly developed molecular assays have revealed important roles of TEs and viruses in host genome evolution and organization. To update on our current understanding of TE biology and to promote new interdisciplinary strategies for the TE research community, leading experts gathered for the 2nd Uppsala Transposon Symposium on October 4–5, 2018 in Uppsala, Sweden. Using cutting-edge single-molecule and single-cell approaches, research on TEs and other repeats has entered a new era in biological and biomedical research. |
| first_indexed | 2024-12-14T02:33:04Z |
| format | Article |
| id | doaj.art-a3a87d327d6b4070959bd328bee68881 |
| institution | Directory Open Access Journal |
| issn | 1759-8753 |
| language | English |
| last_indexed | 2024-12-14T02:33:04Z |
| publishDate | 2018-12-01 |
| publisher | BMC |
| record_format | Article |
| series | Mobile DNA |
| spelling | doaj.art-a3a87d327d6b4070959bd328bee688812022-12-21T23:20:11ZengBMCMobile DNA1759-87532018-12-01911410.1186/s13100-018-0140-5Bridging gaps in transposable element research with single-molecule and single-cell technologiesClaudia Kutter0Patric Jern1Alexander Suh2Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, Science for Life LaboratoryScience for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala UniversityDepartment of Evolutionary Biology, Evolutionary Biology Centre, Science for Life Laboratory, Uppsala UniversityAbstract More than half of the genomic landscape in humans and many other organisms is composed of repetitive DNA, which mostly derives from transposable elements (TEs) and viruses. Recent technological advances permit improved assessment of the repetitive content across genomes and newly developed molecular assays have revealed important roles of TEs and viruses in host genome evolution and organization. To update on our current understanding of TE biology and to promote new interdisciplinary strategies for the TE research community, leading experts gathered for the 2nd Uppsala Transposon Symposium on October 4–5, 2018 in Uppsala, Sweden. Using cutting-edge single-molecule and single-cell approaches, research on TEs and other repeats has entered a new era in biological and biomedical research.http://link.springer.com/article/10.1186/s13100-018-0140-5Transposable elementsRepetitive sequenceEndogenous virusesSatellitesCentromeresEvolution |
| spellingShingle | Claudia Kutter Patric Jern Alexander Suh Bridging gaps in transposable element research with single-molecule and single-cell technologies Mobile DNA Transposable elements Repetitive sequence Endogenous viruses Satellites Centromeres Evolution |
| title | Bridging gaps in transposable element research with single-molecule and single-cell technologies |
| title_full | Bridging gaps in transposable element research with single-molecule and single-cell technologies |
| title_fullStr | Bridging gaps in transposable element research with single-molecule and single-cell technologies |
| title_full_unstemmed | Bridging gaps in transposable element research with single-molecule and single-cell technologies |
| title_short | Bridging gaps in transposable element research with single-molecule and single-cell technologies |
| title_sort | bridging gaps in transposable element research with single molecule and single cell technologies |
| topic | Transposable elements Repetitive sequence Endogenous viruses Satellites Centromeres Evolution |
| url | http://link.springer.com/article/10.1186/s13100-018-0140-5 |
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