Antiviral Potential of Melissa officinalis L.: A Literature Review

The use of synthetic drugs has increased in recent years; however, herbal medicine is yet more trusted among a huge population worldwide; This could be due to minimal side effects, affordable prices, and traditional beliefs. Lemongrass ( Melissa officinalis ) has been widely used for reducing stress...

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Main Authors: Amirhossein Behzadi, Sadegh imani, Niloofar Deravi, Zahra Mohammad Taheri, fatemeh mohammadian, zahra moraveji, Sepideh Shavysi, Motahareh Mostafaloo, Fateme Soleimani Hadidi, Sepehr Nanbakhsh, Sepehr Olangian-Tehrani, Mohammad Hesam Marabi, Parisa behshood, Mohadeseh Poudineh, Ali Kheirandish, Kimia Keylani, Pooya Behfarnia
Format: Article
Language:English
Published: SAGE Publishing 2023-01-01
Series:Nutrition and Metabolic Insights
Online Access:https://doi.org/10.1177/11786388221146683
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author Amirhossein Behzadi
Sadegh imani
Niloofar Deravi
Zahra Mohammad Taheri
fatemeh mohammadian
zahra moraveji
Sepideh Shavysi
Motahareh Mostafaloo
Fateme Soleimani Hadidi
Sepehr Nanbakhsh
Sepehr Olangian-Tehrani
Mohammad Hesam Marabi
Parisa behshood
Mohadeseh Poudineh
Ali Kheirandish
Kimia Keylani
Pooya Behfarnia
author_facet Amirhossein Behzadi
Sadegh imani
Niloofar Deravi
Zahra Mohammad Taheri
fatemeh mohammadian
zahra moraveji
Sepideh Shavysi
Motahareh Mostafaloo
Fateme Soleimani Hadidi
Sepehr Nanbakhsh
Sepehr Olangian-Tehrani
Mohammad Hesam Marabi
Parisa behshood
Mohadeseh Poudineh
Ali Kheirandish
Kimia Keylani
Pooya Behfarnia
author_sort Amirhossein Behzadi
collection DOAJ
description The use of synthetic drugs has increased in recent years; however, herbal medicine is yet more trusted among a huge population worldwide; This could be due to minimal side effects, affordable prices, and traditional beliefs. Lemongrass ( Melissa officinalis ) has been widely used for reducing stress and anxiety, increasing appetite and sleep, reducing pain, healing wounds, and treating poisonous insect bites and bee stings for a long time. Today, research has shown that this plant can also fight viruses including Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), Herpes Simplex Virus (HSV), and Human Immunodeficiency Virus (HIV) through various mechanisms such as inhibiting HSV-1 from binding to host cell, inhibiting HSV-1 replication during the post-adsorption or inhibiting main protease and spike protein of SARS-CoV-2, furthermore, be effective in treating related diseases. This Review investigated the antiviral properties of Melissa officinalis and its effect on viral diseases. More in vitro and in vivo studies are needed to determine Melissa officinaliss underlying mechanism, and more randomized controlled trials should be done to identify its effect in humans. Also, due to the usefulness and lack of side effects, it can be used more as a complementary medicine.
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spelling doaj.art-a3a9138356d0493da874966438bb25622023-01-12T13:33:38ZengSAGE PublishingNutrition and Metabolic Insights1178-63882023-01-011610.1177/11786388221146683Antiviral Potential of Melissa officinalis L.: A Literature ReviewAmirhossein Behzadi0Sadegh imani1Niloofar Deravi2Zahra Mohammad Taheri3fatemeh mohammadian4zahra moraveji5Sepideh Shavysi6Motahareh Mostafaloo7Fateme Soleimani Hadidi8Sepehr Nanbakhsh9Sepehr Olangian-Tehrani10Mohammad Hesam Marabi11Parisa behshood12Mohadeseh Poudineh13Ali Kheirandish14Kimia Keylani15Pooya Behfarnia16Avicennet, Tehran, IranStudent Research Committee, Kurdistan University of Medical Sciences, Sanandaj, IranStudent Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, IranHamedan University of Medical Sciences and Health Services, Hamedan, IranStudent Research Committee, International Campus, Shahid Sadoughi University of Medical Sciences, Yazd, IranStudent Research Committee, International Campus, Shahid Sadoughi University of Medical Sciences, Yazd, IranStudent Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, IranSchool of Nursing and Midwifery, Iran University of Medical Science, Tehran, IranStudent Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, IranAvicennet, Tehran, IranAvicennet, Tehran, IranStudent Research Committee, School of Dentistry, Kermanshah University of Medical Sciences, Kermanshah, IranDepartment of Microbiology, Young Researchers and Elite Club, Shahrekord Branch, Islamic Azad University, Isfahan, IranSchool of Medicine, Zanjan University of Medical Sciences, Zanjan, IranStudent Research Committee, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, IranSchool of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, IranSchool of Medicine, Isfahan University of Medical Sciences, Isfahan, IranThe use of synthetic drugs has increased in recent years; however, herbal medicine is yet more trusted among a huge population worldwide; This could be due to minimal side effects, affordable prices, and traditional beliefs. Lemongrass ( Melissa officinalis ) has been widely used for reducing stress and anxiety, increasing appetite and sleep, reducing pain, healing wounds, and treating poisonous insect bites and bee stings for a long time. Today, research has shown that this plant can also fight viruses including Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), Herpes Simplex Virus (HSV), and Human Immunodeficiency Virus (HIV) through various mechanisms such as inhibiting HSV-1 from binding to host cell, inhibiting HSV-1 replication during the post-adsorption or inhibiting main protease and spike protein of SARS-CoV-2, furthermore, be effective in treating related diseases. This Review investigated the antiviral properties of Melissa officinalis and its effect on viral diseases. More in vitro and in vivo studies are needed to determine Melissa officinaliss underlying mechanism, and more randomized controlled trials should be done to identify its effect in humans. Also, due to the usefulness and lack of side effects, it can be used more as a complementary medicine.https://doi.org/10.1177/11786388221146683
spellingShingle Amirhossein Behzadi
Sadegh imani
Niloofar Deravi
Zahra Mohammad Taheri
fatemeh mohammadian
zahra moraveji
Sepideh Shavysi
Motahareh Mostafaloo
Fateme Soleimani Hadidi
Sepehr Nanbakhsh
Sepehr Olangian-Tehrani
Mohammad Hesam Marabi
Parisa behshood
Mohadeseh Poudineh
Ali Kheirandish
Kimia Keylani
Pooya Behfarnia
Antiviral Potential of Melissa officinalis L.: A Literature Review
Nutrition and Metabolic Insights
title Antiviral Potential of Melissa officinalis L.: A Literature Review
title_full Antiviral Potential of Melissa officinalis L.: A Literature Review
title_fullStr Antiviral Potential of Melissa officinalis L.: A Literature Review
title_full_unstemmed Antiviral Potential of Melissa officinalis L.: A Literature Review
title_short Antiviral Potential of Melissa officinalis L.: A Literature Review
title_sort antiviral potential of melissa officinalis l a literature review
url https://doi.org/10.1177/11786388221146683
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