Plexiform Fibrohistiocytic Tumour at a Rare Site: Frontal Region of Head with underlying Frontal Bone Invasion
Plexiform Fibrohistiocytic Tumour (PFHT) is an intermediate malignant tumour of soft tissue. It is a rarely metastasising dermal subcutaneous neoplasm. It affects children and young adults. The age range of presentation is from birth to age 77 years. The tumour is most commonly located on the upper...
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JCDR Research and Publications Private Limited
2022-06-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://www.jcdr.net/articles/PDF/16427/53777_F(KM)_PF1(SM_SHU)_PFA(SM_KM)_PN(KM).pdf |
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| author | Sarita Nibhoria Ekta Rani Aradhana Singh Hada Bikramjit Singh Ruth Prakash |
| author_facet | Sarita Nibhoria Ekta Rani Aradhana Singh Hada Bikramjit Singh Ruth Prakash |
| author_sort | Sarita Nibhoria |
| collection | DOAJ |
| description | Plexiform Fibrohistiocytic Tumour (PFHT) is an intermediate malignant tumour of soft tissue. It is a rarely metastasising dermal subcutaneous neoplasm. It affects children and young adults. The age range of presentation is from birth to age 77 years. The tumour is most commonly located on the upper extremities, whereas the involvement of the frontal region is rare. The differential diagnosis includes benign fibrous histiocytoma, fibromatosis, giant cell tumour and neurofibroma. Plexiform fibrohistiocytic tumour is a slow-growing mass and which is considered a low grade malignant tumour. Treatment is simple excision. It can exhibit aggressive behaviour and rate of local recurrence is 12-38%. A 45-year-old female was presented with a solid mass on the frontal region of the head which was diagnosed as a plexiform fibrohistiocytic tumour with underlying frontal bone invasion on histopathological examination of an excised mass in the Pathology Department. Plexiform Fibrohistiocytic Tumour (PFHT) is a mesenchymal neoplasm that shows a multinodular growth pattern and which is composed of fibroblasts, histiocyte like cells and multinucleated osteoclast like giant cells. Clinically, it is usually a slow-growing mass with frequent local recurrence and rare regional lymphatic and systemic metastasis. |
| first_indexed | 2024-04-10T15:29:22Z |
| format | Article |
| id | doaj.art-a3a9b47d6e614b14ae82542d9a897f58 |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-04-10T15:29:22Z |
| publishDate | 2022-06-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-a3a9b47d6e614b14ae82542d9a897f582023-02-14T06:30:04ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2022-06-01166ED01ED0210.7860/JCDR/2022/53777.16427Plexiform Fibrohistiocytic Tumour at a Rare Site: Frontal Region of Head with underlying Frontal Bone InvasionSarita Nibhoria0Ekta Rani1Aradhana Singh Hada2Bikramjit Singh3Ruth Prakash4Professor and Head, Department of Pathology, Guru Gobind Singh Medical College and Hospital, Faridkot, Punjab, India.Assistant Professor, Department of Pathology, Guru Gobind Singh Medical College and Hospital, Faridkot, Punjab, India.Senior Resident, Department of Pathology, Guru Gobind Singh Medical College and Hospital, Faridkot, Punjab, India.Junior Resident, Department of Pathology, Guru Gobind Singh Medical College and Hospital, Faridkot, Punjab, India.Junior Resident, Department of Pathology, Guru Gobind Singh Medical College and Hospital, Faridkot, Punjab, India.Plexiform Fibrohistiocytic Tumour (PFHT) is an intermediate malignant tumour of soft tissue. It is a rarely metastasising dermal subcutaneous neoplasm. It affects children and young adults. The age range of presentation is from birth to age 77 years. The tumour is most commonly located on the upper extremities, whereas the involvement of the frontal region is rare. The differential diagnosis includes benign fibrous histiocytoma, fibromatosis, giant cell tumour and neurofibroma. Plexiform fibrohistiocytic tumour is a slow-growing mass and which is considered a low grade malignant tumour. Treatment is simple excision. It can exhibit aggressive behaviour and rate of local recurrence is 12-38%. A 45-year-old female was presented with a solid mass on the frontal region of the head which was diagnosed as a plexiform fibrohistiocytic tumour with underlying frontal bone invasion on histopathological examination of an excised mass in the Pathology Department. Plexiform Fibrohistiocytic Tumour (PFHT) is a mesenchymal neoplasm that shows a multinodular growth pattern and which is composed of fibroblasts, histiocyte like cells and multinucleated osteoclast like giant cells. Clinically, it is usually a slow-growing mass with frequent local recurrence and rare regional lymphatic and systemic metastasis.https://www.jcdr.net/articles/PDF/16427/53777_F(KM)_PF1(SM_SHU)_PFA(SM_KM)_PN(KM).pdfhistocyte like cellslow grade tumoursmesenchymal tumourosteoclast like giant cells |
| spellingShingle | Sarita Nibhoria Ekta Rani Aradhana Singh Hada Bikramjit Singh Ruth Prakash Plexiform Fibrohistiocytic Tumour at a Rare Site: Frontal Region of Head with underlying Frontal Bone Invasion Journal of Clinical and Diagnostic Research histocyte like cells low grade tumours mesenchymal tumour osteoclast like giant cells |
| title | Plexiform Fibrohistiocytic Tumour at a Rare Site: Frontal Region of Head with underlying Frontal Bone Invasion |
| title_full | Plexiform Fibrohistiocytic Tumour at a Rare Site: Frontal Region of Head with underlying Frontal Bone Invasion |
| title_fullStr | Plexiform Fibrohistiocytic Tumour at a Rare Site: Frontal Region of Head with underlying Frontal Bone Invasion |
| title_full_unstemmed | Plexiform Fibrohistiocytic Tumour at a Rare Site: Frontal Region of Head with underlying Frontal Bone Invasion |
| title_short | Plexiform Fibrohistiocytic Tumour at a Rare Site: Frontal Region of Head with underlying Frontal Bone Invasion |
| title_sort | plexiform fibrohistiocytic tumour at a rare site frontal region of head with underlying frontal bone invasion |
| topic | histocyte like cells low grade tumours mesenchymal tumour osteoclast like giant cells |
| url | https://www.jcdr.net/articles/PDF/16427/53777_F(KM)_PF1(SM_SHU)_PFA(SM_KM)_PN(KM).pdf |
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