Hematopoietic stem and progenitor cells confer cross-protective trained immunity in mouse models
Summary: Recent studies suggest that infection reprograms hematopoietic stem and progenitor cells (HSPCs) to enhance innate immune responses upon secondary infectious challenge, a process called “trained immunity.” However, the specificity and cell types responsible for this response remain poorly d...
Main Authors: | Bailee N. Kain, Brandon T. Tran, Pamela N. Luna, Ruoqiong Cao, Duy T. Le, Marcus A. Florez, Laure Maneix, Jack D. Toups, Daniel E. Morales-Mantilla, Scott Koh, Hyojeong Han, Roman Jaksik, Yun Huang, Andre Catic, Chad A. Shaw, Katherine Y. King |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-09-01
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Series: | iScience |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004223016735 |
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