A hidden Markov model for haplotype inference for present-absent data of clustered genes using identified haplotypes and haplotype patterns

A hidden Markov model for haplotype inference for present-absent data of clustered genes using identified haplotypes and haplotype patterns

The majority of killer cell immunoglobin-like receptor (KIR) genes are detected as either present or absent using locus-specific genotyping technology. Ambiguity arises from the presence of a specific KIR gene since the exact copy number (one or two) of that gene is unknown. Therefore, haplotype inf...

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Bibliographic Details
Main Authors: KUI eZHANG, Jihua eWu, Guo-bo eChen, Degui eZhi, Nianjun eLiu
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-08-01
Series:Frontiers in Genetics
Subjects:
haplotype
Hidden markov model
haplotype inference
KIR genes
Haplotype Patterns
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00267/full

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