Integrin α10β1-selected mesenchymal stem cells reduced hypercoagulopathy in a porcine model of acute respiratory distress syndrome

Integrin α10β1-selected mesenchymal stem cells reduced hypercoagulopathy in a porcine model of acute respiratory distress syndrome

Abstract Mesenchymal stem cells (MSCs) have been studied for their potential benefits in treating acute respiratory distress syndrome (ARDS) and have reported mild effects when trialed within human clinical trials. MSCs have been investigated in preclinical models with efficacy when administered at...

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Bibliographic Details
Main Authors: Dag Edström, Anna Niroomand, Martin Stenlo, Kristina Uvebrant, Deniz A. Bölükbas, Gabriel Hirdman, Ellen Broberg, Hooi Ching Lim, Snejana Hyllén, Evy Lundgren-Åkerlund, Leif Pierre, Franziska Olm, Sandra Lindstedt
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Respiratory Research
Subjects:
Acute respiratory distress syndrome
Integrin α10β1 mesenchymal stem cells
Lung disease
Advanced therapeutic medicinal products
Online Access:https://doi.org/10.1186/s12931-023-02459-6

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