Ampullary Carcinoma: An Overview of a Rare Entity and Discussion of Current and Future Therapeutic Challenges
Ampullary carcinomas (ACs) represent a rare entity, accounting for approximately 0.2% of all gastrointestinal solid tumors and 20% of all periampullary cancers (PACs). Unfortunately, few data are available regarding the optimal therapeutic strategy for ACs due to their rarity, and physicians frequen...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-09-01
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| Series: | Current Oncology |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1718-7729/28/5/293 |
| _version_ | 1797514879302631424 |
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| author | Alessandro Rizzo Vincenzo Dadduzio Lucia Lombardi Angela Dalia Ricci Gennaro Gadaleta-Caldarola |
| author_facet | Alessandro Rizzo Vincenzo Dadduzio Lucia Lombardi Angela Dalia Ricci Gennaro Gadaleta-Caldarola |
| author_sort | Alessandro Rizzo |
| collection | DOAJ |
| description | Ampullary carcinomas (ACs) represent a rare entity, accounting for approximately 0.2% of all gastrointestinal solid tumors and 20% of all periampullary cancers (PACs). Unfortunately, few data are available regarding the optimal therapeutic strategy for ACs due to their rarity, and physicians frequently encounter significant difficulties in the management of these malignancies. In this review, we will provide an overview of current evidence on AC, especially focusing on biological features, histological characteristics, and available data guiding present and future therapeutic strategies for these rare, and still barely known, tumors. |
| first_indexed | 2024-03-10T06:38:47Z |
| format | Article |
| id | doaj.art-a3ac9ac9a7c440cb99b9c5445e4faf79 |
| institution | Directory Open Access Journal |
| issn | 1198-0052 1718-7729 |
| language | English |
| last_indexed | 2024-03-10T06:38:47Z |
| publishDate | 2021-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Current Oncology |
| spelling | doaj.art-a3ac9ac9a7c440cb99b9c5445e4faf792023-11-22T17:54:30ZengMDPI AGCurrent Oncology1198-00521718-77292021-09-012853393340210.3390/curroncol28050293Ampullary Carcinoma: An Overview of a Rare Entity and Discussion of Current and Future Therapeutic ChallengesAlessandro Rizzo0Vincenzo Dadduzio1Lucia Lombardi2Angela Dalia Ricci3Gennaro Gadaleta-Caldarola4Medical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Albertoni-15, 40128 Bologna, ItalyMedical Oncology Unit, “Mons. R. Dimiccoli” Hospital, 76121 Barletta (BT), ASL BT, ItalyMedical Oncology Unit, “Mons. R. Dimiccoli” Hospital, 76121 Barletta (BT), ASL BT, ItalyMedical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Albertoni-15, 40128 Bologna, ItalyMedical Oncology Unit, “Mons. R. Dimiccoli” Hospital, 76121 Barletta (BT), ASL BT, ItalyAmpullary carcinomas (ACs) represent a rare entity, accounting for approximately 0.2% of all gastrointestinal solid tumors and 20% of all periampullary cancers (PACs). Unfortunately, few data are available regarding the optimal therapeutic strategy for ACs due to their rarity, and physicians frequently encounter significant difficulties in the management of these malignancies. In this review, we will provide an overview of current evidence on AC, especially focusing on biological features, histological characteristics, and available data guiding present and future therapeutic strategies for these rare, and still barely known, tumors.https://www.mdpi.com/1718-7729/28/5/293ampullary cancerampulla of Vater cancerbiliary tract cancerchemotherapyadenocarcinoma |
| spellingShingle | Alessandro Rizzo Vincenzo Dadduzio Lucia Lombardi Angela Dalia Ricci Gennaro Gadaleta-Caldarola Ampullary Carcinoma: An Overview of a Rare Entity and Discussion of Current and Future Therapeutic Challenges Current Oncology ampullary cancer ampulla of Vater cancer biliary tract cancer chemotherapy adenocarcinoma |
| title | Ampullary Carcinoma: An Overview of a Rare Entity and Discussion of Current and Future Therapeutic Challenges |
| title_full | Ampullary Carcinoma: An Overview of a Rare Entity and Discussion of Current and Future Therapeutic Challenges |
| title_fullStr | Ampullary Carcinoma: An Overview of a Rare Entity and Discussion of Current and Future Therapeutic Challenges |
| title_full_unstemmed | Ampullary Carcinoma: An Overview of a Rare Entity and Discussion of Current and Future Therapeutic Challenges |
| title_short | Ampullary Carcinoma: An Overview of a Rare Entity and Discussion of Current and Future Therapeutic Challenges |
| title_sort | ampullary carcinoma an overview of a rare entity and discussion of current and future therapeutic challenges |
| topic | ampullary cancer ampulla of Vater cancer biliary tract cancer chemotherapy adenocarcinoma |
| url | https://www.mdpi.com/1718-7729/28/5/293 |
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