The Synthesis of Triazolium Salts as Antifungal Agents: A Biological and In Silico Evaluation

The Synthesis of Triazolium Salts as Antifungal Agents: A Biological and In Silico Evaluation

The control of fungal pathogens is increasingly difficult due to the limited number of effective drugs available for antifungal therapy. In addition, both humans and fungi are eukaryotic organisms; antifungal drugs may have significant toxicity due to the inhibition of related human targets. Further...

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Main Authors: Serghei Pogrebnoi, Oleg Radul, Eugenia Stingaci, Lucian Lupascu, Vladimir Valica, Livia Uncu, Anastasia Smetanscaia, Anthi Petrou, Ana Ćirić, Jasmina Glamočlija, Marina Soković, Athina Geronikaki, Fliur Z. Macaev
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Antibiotics
Subjects:
triazolium salts
antifungal
microdilution method
docking
CYP51
Online Access:https://www.mdpi.com/2079-6382/11/5/588

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