Sleep quality among psoriasis patients: excluding the immunosuppressive therapy effect
Abstract Background Psoriasis is associated with several comorbidities and different psychological disorders including anxiety and depression. Psoriasis may also affect sleep quality and consequently the quality of life. The use of immunosuppressants used in the treatment of psoriasis were also repo...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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SpringerOpen
2023-04-01
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| Series: | Middle East Current Psychiatry |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s43045-023-00305-5 |
| _version_ | 1827970665013051392 |
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| author | Ola O. Khalaf Mohamed M. El-Komy Dina B. Kattaria Marwa S. El-Mesidy |
| author_facet | Ola O. Khalaf Mohamed M. El-Komy Dina B. Kattaria Marwa S. El-Mesidy |
| author_sort | Ola O. Khalaf |
| collection | DOAJ |
| description | Abstract Background Psoriasis is associated with several comorbidities and different psychological disorders including anxiety and depression. Psoriasis may also affect sleep quality and consequently the quality of life. The use of immunosuppressants used in the treatment of psoriasis were also reported to increase insomnia, so the purpose of the study is to assess the quality of sleep and degree of insomnia in patients with psoriasis not on any systemic or immunosuppressive therapy compared to controls and to examine the relation between sleep quality, insomnia with depressive, and anxiety symptoms. One hundred psoriasis cases, not receiving immunosuppressive therapy, and 80 apparently healthy subjects were recruited as controls. We assessed quality of sleep, insomnia and screened for anxiety and depressive symptoms among psoriasis patients and healthy controls; any patient on immunosuppressant therapy was excluded. Results Quality of sleep using Pittsburgh Sleep Quality Index, insomnia using Insomnia Severity Index, depression using Beck Depression Inventory, and anxiety using Taylor Anxiety Manifest Scale were statistically significant higher among psoriasis patients than healthy controls all with p value p < 0.001. Depressive symptoms were significantly positively correlated with Pittsburgh Sleep Quality Index (PSQI) global score (p = 0.045) and subjective sleep quality subscale (p = 0.005). Also, BDI scores was significantly positively correlated with insomnia scores as measured by ISI (p = 0.026). Anxiety symptoms were significantly positively correlated with global score of PSQI (p = 0.004) and its subscale (subjective sleep quality, sleep latency, sleep disturbance, use of medications and daytime dysfunction) and insomnia (p = 0.001). Conclusions Abnormal sleep quality and insomnia were detected in patients with psoriasis not using any immunosuppressive or systemic therapy, and this could be due to the psoriasis disease itself or due to the associated anxiety and depression associated with psoriasis. Screening for psychiatric symptoms specially that of depression, anxiety, and sleep among patients with psoriasis is of utmost importance for better quality of life. Thus, collaboration between dermatologists and psychiatrists may show better life quality for these cases and better treatment outcomes. |
| first_indexed | 2024-04-09T18:57:20Z |
| format | Article |
| id | doaj.art-a3b84840f8154441b3eaf50eafb5c675 |
| institution | Directory Open Access Journal |
| issn | 2090-5416 |
| language | English |
| last_indexed | 2024-04-09T18:57:20Z |
| publishDate | 2023-04-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Middle East Current Psychiatry |
| spelling | doaj.art-a3b84840f8154441b3eaf50eafb5c6752023-04-09T11:06:54ZengSpringerOpenMiddle East Current Psychiatry2090-54162023-04-013011810.1186/s43045-023-00305-5Sleep quality among psoriasis patients: excluding the immunosuppressive therapy effectOla O. Khalaf0Mohamed M. El-Komy1Dina B. Kattaria2Marwa S. El-Mesidy3Psychiatry Department, Kasr Al Ainy Faculty of Medicine Cairo UniversityDermatology Department, Kasr Al Ainy Faculty of Medicine Cairo UniversityPsychiatry Department, Kasr Al Ainy Faculty of Medicine Cairo UniversityDermatology Department, Kasr Al Ainy Faculty of Medicine Cairo UniversityAbstract Background Psoriasis is associated with several comorbidities and different psychological disorders including anxiety and depression. Psoriasis may also affect sleep quality and consequently the quality of life. The use of immunosuppressants used in the treatment of psoriasis were also reported to increase insomnia, so the purpose of the study is to assess the quality of sleep and degree of insomnia in patients with psoriasis not on any systemic or immunosuppressive therapy compared to controls and to examine the relation between sleep quality, insomnia with depressive, and anxiety symptoms. One hundred psoriasis cases, not receiving immunosuppressive therapy, and 80 apparently healthy subjects were recruited as controls. We assessed quality of sleep, insomnia and screened for anxiety and depressive symptoms among psoriasis patients and healthy controls; any patient on immunosuppressant therapy was excluded. Results Quality of sleep using Pittsburgh Sleep Quality Index, insomnia using Insomnia Severity Index, depression using Beck Depression Inventory, and anxiety using Taylor Anxiety Manifest Scale were statistically significant higher among psoriasis patients than healthy controls all with p value p < 0.001. Depressive symptoms were significantly positively correlated with Pittsburgh Sleep Quality Index (PSQI) global score (p = 0.045) and subjective sleep quality subscale (p = 0.005). Also, BDI scores was significantly positively correlated with insomnia scores as measured by ISI (p = 0.026). Anxiety symptoms were significantly positively correlated with global score of PSQI (p = 0.004) and its subscale (subjective sleep quality, sleep latency, sleep disturbance, use of medications and daytime dysfunction) and insomnia (p = 0.001). Conclusions Abnormal sleep quality and insomnia were detected in patients with psoriasis not using any immunosuppressive or systemic therapy, and this could be due to the psoriasis disease itself or due to the associated anxiety and depression associated with psoriasis. Screening for psychiatric symptoms specially that of depression, anxiety, and sleep among patients with psoriasis is of utmost importance for better quality of life. Thus, collaboration between dermatologists and psychiatrists may show better life quality for these cases and better treatment outcomes.https://doi.org/10.1186/s43045-023-00305-5PsoriasisSleep qualityInsomniaAnxietyDepression |
| spellingShingle | Ola O. Khalaf Mohamed M. El-Komy Dina B. Kattaria Marwa S. El-Mesidy Sleep quality among psoriasis patients: excluding the immunosuppressive therapy effect Middle East Current Psychiatry Psoriasis Sleep quality Insomnia Anxiety Depression |
| title | Sleep quality among psoriasis patients: excluding the immunosuppressive therapy effect |
| title_full | Sleep quality among psoriasis patients: excluding the immunosuppressive therapy effect |
| title_fullStr | Sleep quality among psoriasis patients: excluding the immunosuppressive therapy effect |
| title_full_unstemmed | Sleep quality among psoriasis patients: excluding the immunosuppressive therapy effect |
| title_short | Sleep quality among psoriasis patients: excluding the immunosuppressive therapy effect |
| title_sort | sleep quality among psoriasis patients excluding the immunosuppressive therapy effect |
| topic | Psoriasis Sleep quality Insomnia Anxiety Depression |
| url | https://doi.org/10.1186/s43045-023-00305-5 |
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