Development of a Multiplex Sandwich Aptamer Microarray for the Detection of VEGF165 and Thrombin

Development of a Multiplex Sandwich Aptamer Microarray for the Detection of VEGF165 and Thrombin

In this work we have developed a multiplex microarray system capable of detecting VEGF165 and thrombin. We recently described a Sandwich Aptamer Microarray (SAM) for thrombin detection feasible for use in multiplex microarrays; here we describe a new aptasensor for VEGF165 detection employing Vap7 a...

Полное описание

Библиографические подробности
Главные авторы:	Anna Meneghello, Barbara Gatto, Agnese Antognoli, Erica Cretaio, Alice Sosic
Формат:	Статья
Язык:	English
Опубликовано:	MDPI AG 2013-10-01
Серии:	Sensors
Предметы:	VEGF thrombin aptamers sandwich aptamer-microarray angiogenesis
Online-ссылка:	http://www.mdpi.com/1424-8220/13/10/13425

Схожие документы

Human Thrombin Detection Through a Sandwich Aptamer Microarray: Interaction Analysis in Solution and in Solid Phase
по: Alice Sosic, и др.
Опубликовано: (2011-10-01)

Aptamer-Based Sensors for Thrombin Detection Application
по: Hongzhi Sun, и др.
Опубликовано: (2022-06-01)

Construction of a Bivalent Thrombin Binding Aptamer and Its Antidote with Improved Properties
по: Quintin W. Hughes, и др.
Опубликовано: (2017-10-01)

Design strategy of antidote sequence for bivalent aptamer: Rapid neutralization of high‐anticoagulant thrombin‐binding bivalent DNA aptamer‐linked M08 with HD22
по: Toru Yoshitomi, и др.
Опубликовано: (2021-07-01)

Aptamer Based Microsphere Biosensor for Thrombin Detection
по: Xudong Fan, и др.
Опубликовано: (2006-08-01)

Thermodynamic, Anticoagulant, and Antiproliferative Properties of Thrombin Binding Aptamer Containing Novel UNA Derivative
по: Weronika Kotkowiak, и др.
Опубликовано: (2018-03-01)

Dual Aptamer-Functionalized 3D Plasmonic Metamolecule for Thrombin Sensing
по: Timon Funck, и др.
Опубликовано: (2019-07-01)

New High-Affinity Thrombin Aptamers for Advancing Coagulation Therapy: Balancing Thrombin Inhibition for Clot Prevention and Effective Bleeding Management with Antidote
по: Mohamad Ammar Ayass, и др.
Опубликовано: (2023-09-01)

A fluorescence kinetic-based aptasensor employing stilbene isomerization for detection of thrombin
по: Zeng, Xinling, и др.
Опубликовано: (2021)

Structural and Binding Effects of Chemical Modifications on Thrombin Binding Aptamer (TBA)
по: Vibhav Valsangkar, и др.
Опубликовано: (2021-07-01)

Aptamer-Based Nanoporous Anodic Alumina Interferometric Biosensor for Real-Time Thrombin Detection
по: Laura Pol, и др.
Опубликовано: (2019-10-01)

In situ amplification based on assembly of aptamer sandwiches on nanochannels for ultrasensitive detection of exosomes
по: Yue Huang, и др.
Опубликовано: (2023-11-01)

Screening and Improvement of an Anti-VEGF DNA Aptamer
по: Kazunori Ikebukuro, и др.
Опубликовано: (2010-01-01)

Docking Simulation and Sandwich Assay for Aptamer-Based Botulinum Neurotoxin Type C Detection
по: In-Hwan Oh, и др.
Опубликовано: (2020-08-01)

The Regioselective Conjugation of the 15-nt Thrombin Aptamer with an Optimized Tripeptide Sequence Greatly Increases the Anticoagulant Activity of the Aptamer
по: Irina V. Varizhuk, и др.
Опубликовано: (2023-02-01)

Comparison of Effects of Anti-thrombin Aptamers HD1 and HD22 on Aggregation of Human Platelets, Thrombin Generation, Fibrin Formation, and Thrombus Formation Under Flow Conditions
по: Katarzyna Derszniak, и др.
Опубликовано: (2019-02-01)

Aptamer functionalized fluorescent probe for detection of thrombin in human serum via static quenching
по: Penghui Hu, и др.
Опубликовано: (2024-02-01)

Energy Dissipation Hypothesis Applied to Enhance the Affinity of Thrombin Binding Aptamer
по: Gleb Zhdanov, и др.
Опубликовано: (2021-05-01)

Detection of Thrombin Based on Fluorescence Energy Transfer between Semiconducting Polymer Dots and BHQ-Labelled Aptamers
по: Yizhang Liu, и др.
Опубликовано: (2018-02-01)

Systematic design and evaluation of aptamers for VEGF and PlGF biomarkers of Preeclampsia
по: Samavath Mallawarachchi, и др.
Опубликовано: (2024-09-01)

Electrochemical Sandwich Assays for Biomarkers Incorporating Aptamers, Antibodies and Nanomaterials for Detection of Specific Protein Biomarkers
по: Dharmendra Neupane, и др.
Опубликовано: (2021-07-01)

Design of Potent and Controllable Anticoagulants Using DNA Aptamers and Nanostructures
по: Abhijit Rangnekar, и др.
Опубликовано: (2016-02-01)

A neutralizable dimeric anti-thrombin aptamer with potent anticoagulant activity in mice
по: Masanobu Nagano, и др.
Опубликовано: (2023-09-01)

Recognition Interface of the Thrombin Binding Aptamer Requires Antiparallel Topology of the Quadruplex Core
по: Julia Svetlova, и др.
Опубликовано: (2021-09-01)

A Stable Biotin-Streptavidin Surface Enables Multiplex, Label-Free Protein Detection by Aptamer and Aptamer-Protein Arrays Using Arrayed Imaging Reflectometry
по: Alanna M. Klose, и др.
Опубликовано: (2020-10-01)

Systematic selection of modified aptamer pairs for diagnostic sandwich assays
по: Urs A. Ochsner, и др.
Опубликовано: (2014-03-01)

Exploring potential anticoagulant drug formulations using thrombin generation test
по: Elena Zavyalova, и др.
Опубликовано: (2016-03-01)

Recent Progresses in Development of Biosensors for Thrombin Detection
по: Reza Eivazzadeh-Keihan, и др.
Опубликовано: (2022-09-01)

One-Step Facile Synthesis of Aptamer-Modified Graphene Oxide for Highly Specific Enrichment of Human A-Thrombin in Plasma
по: Yuan Xu, и др.
Опубликовано: (2017-09-01)

The Application of Microfluidic Technologies in Aptamer Selection
по: Yang Liu, и др.
Опубликовано: (2021-09-01)

Development of Aptamer-Based TID Assays Using Thermophoresis and Microarrays
по: Tracy Kurth, и др.
Опубликовано: (2019-10-01)

A Reusable Impedimetric Aptasensor for Detection of Thrombin Employing a Graphite-Epoxy Composite Electrode
по: Manel del Valle, и др.
Опубликовано: (2012-03-01)

Etched Fiber Bragg Grating Biosensor Functionalized with Aptamers for Detection of Thrombin
по: Aliya Bekmurzayeva, и др.
Опубликовано: (2018-12-01)

A Comprehensive Analysis of the Thrombin Binding Aptamer Containing Functionalized Pyrrolo-2’-deoxycytidines
по: Weronika Kotkowiak, и др.
Опубликовано: (2021-12-01)

DNA module platform for developing colorimetric aptamer sensors
по: Yasuyuki Tomita, и др.
Опубликовано: (2016-06-01)

Rational design of a structure-switching DNA aptamer for potassium ions
по: Andrew T. Catherine, и др.
Опубликовано: (2014-01-01)

Kinetic Exclusion Assay of Biomolecules by Aptamer Capture
по: Mark H. Smith, и др.
Опубликовано: (2020-06-01)

A Guided Mode Resonance Aptasensor for Thrombin Detection
по: Wen-Yih Chen, и др.
Опубликовано: (2011-09-01)

Highly Sensitive Colorimetric Assay of Cortisol Using Cortisol Antibody and Aptamer Sandwich Assay
по: Yoonjae Kim, и др.
Опубликовано: (2021-05-01)

PC Deficiency Testing: Thrombin-Thrombomodulin as PC Activator and Aptamer-Based Enzyme Capturing Increase Diagnostic Accuracy
по: Sara Reda, и др.
Опубликовано: (2021-10-01)