Prediction of fibril formation by early-stage amyloid peptide aggregation

Amyloid fibrils are found in systemic amyloidosis diseases such as Alzheimer’s disease, Parkinson’s disease, and type II diabetes. Currently, these diseases are diagnosed by observation of fibrils or plaques, which is an ineffective method for early diagnosis and treatment of disease. The goal of th...

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Bibliographic Details
Main Authors: Jiaojiao Hu, Huiyong Sun, Haiping Hao, Qiuling Zheng
Format: Article
Language:English
Published: Elsevier 2020-04-01
Series:Journal of Pharmaceutical Analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2095177919305817