Approach to hematopoietic cell transplant candidates with respiratory viral detection
The management of respiratory viruses prior to hematopoietic cell transplant (HCT) can be controversial and requires special consideration of host factors, transplant parameters, and the specific respiratory virus (RV). In the setting of adenovirus (ADV), human metapneumovirus (HMPV), influenza, par...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-01-01
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| Series: | Frontiers in Pediatrics |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fped.2023.1339239/full |
| _version_ | 1827379566725824512 |
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| author | Sara R. Kim Sara R. Kim Alpana Waghmare Alpana Waghmare Alpana Waghmare Diego R. Hijano Diego R. Hijano |
| author_facet | Sara R. Kim Sara R. Kim Alpana Waghmare Alpana Waghmare Alpana Waghmare Diego R. Hijano Diego R. Hijano |
| author_sort | Sara R. Kim |
| collection | DOAJ |
| description | The management of respiratory viruses prior to hematopoietic cell transplant (HCT) can be controversial and requires special consideration of host factors, transplant parameters, and the specific respiratory virus (RV). In the setting of adenovirus (ADV), human metapneumovirus (HMPV), influenza, parainfluenza virus (PIV), and respiratory syncytial virus (RSV) detection prior to hematopoietic cell transplant (HCT), clinical practice guidelines recommend transplant delay when possible; however, there is much more ambiguity when other respiratory viruses, such as seasonal coronaviruses (CoVs), human rhinovirus (HRV), and SARS-CoV-2, are detected. Our aims for this review include detailing clinical practical guidelines and reviewing current literature on pre-transplant respiratory viral infections (RVIs), including antiviral therapies and prevention strategies, when available. We will center our discussion on three representative clinical scenarios, with the goal of providing practical guidance to clinicians. |
| first_indexed | 2024-03-08T13:18:47Z |
| format | Article |
| id | doaj.art-a3c12addee034a928f3c42c48b546e25 |
| institution | Directory Open Access Journal |
| issn | 2296-2360 |
| language | English |
| last_indexed | 2024-03-08T13:18:47Z |
| publishDate | 2024-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pediatrics |
| spelling | doaj.art-a3c12addee034a928f3c42c48b546e252024-01-18T04:27:15ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602024-01-011110.3389/fped.2023.13392391339239Approach to hematopoietic cell transplant candidates with respiratory viral detectionSara R. Kim0Sara R. Kim1Alpana Waghmare2Alpana Waghmare3Alpana Waghmare4Diego R. Hijano5Diego R. Hijano6Division of Pediatric Infectious Diseases, Seattle Children’s Hospital, Seattle, WA, United StatesDepartment of Pediatrics, University of Washington, Seattle, WA, United StatesDivision of Pediatric Infectious Diseases, Seattle Children’s Hospital, Seattle, WA, United StatesDepartment of Pediatrics, University of Washington, Seattle, WA, United StatesVaccine and Infectious Diseases Division, Fred Hutchinson Cancer Center, Seattle, WA, United StatesDepartments of Infectious Diseases, St. Jude Children’s Research Hospital, Memphis, TN, United StatesDepartment of Pediatrics, University of Tennessee Health Sciences Center, Memphis, TN, United StatesThe management of respiratory viruses prior to hematopoietic cell transplant (HCT) can be controversial and requires special consideration of host factors, transplant parameters, and the specific respiratory virus (RV). In the setting of adenovirus (ADV), human metapneumovirus (HMPV), influenza, parainfluenza virus (PIV), and respiratory syncytial virus (RSV) detection prior to hematopoietic cell transplant (HCT), clinical practice guidelines recommend transplant delay when possible; however, there is much more ambiguity when other respiratory viruses, such as seasonal coronaviruses (CoVs), human rhinovirus (HRV), and SARS-CoV-2, are detected. Our aims for this review include detailing clinical practical guidelines and reviewing current literature on pre-transplant respiratory viral infections (RVIs), including antiviral therapies and prevention strategies, when available. We will center our discussion on three representative clinical scenarios, with the goal of providing practical guidance to clinicians.https://www.frontiersin.org/articles/10.3389/fped.2023.1339239/fullrespiratory viruschildrenimmunocompromisedcancerhematopoietic cell transplant |
| spellingShingle | Sara R. Kim Sara R. Kim Alpana Waghmare Alpana Waghmare Alpana Waghmare Diego R. Hijano Diego R. Hijano Approach to hematopoietic cell transplant candidates with respiratory viral detection Frontiers in Pediatrics respiratory virus children immunocompromised cancer hematopoietic cell transplant |
| title | Approach to hematopoietic cell transplant candidates with respiratory viral detection |
| title_full | Approach to hematopoietic cell transplant candidates with respiratory viral detection |
| title_fullStr | Approach to hematopoietic cell transplant candidates with respiratory viral detection |
| title_full_unstemmed | Approach to hematopoietic cell transplant candidates with respiratory viral detection |
| title_short | Approach to hematopoietic cell transplant candidates with respiratory viral detection |
| title_sort | approach to hematopoietic cell transplant candidates with respiratory viral detection |
| topic | respiratory virus children immunocompromised cancer hematopoietic cell transplant |
| url | https://www.frontiersin.org/articles/10.3389/fped.2023.1339239/full |
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