CD73-dependent generation of extracellular adenosine by vascular endothelial cells modulates de novo lipogenesis in adipose tissue

CD73-dependent generation of extracellular adenosine by vascular endothelial cells modulates de novo lipogenesis in adipose tissue

Next to white and brown adipocytes present in white and brown adipose tissue (WAT, BAT), vascular endothelial cells, tissue-resident macrophages and other immune cells have important roles in maintaining adipose tissue homeostasis but also contribute to the etiology of obesity-associated chronic inf...

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Bibliographic Details
Main Authors: Michelle Y. Jaeckstein, Isabell Schulze, Michael Wolfgang Zajac, Markus Heine, Oliver Mann, Alexander Pfeifer, Joerg Heeren
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Immunology
Subjects:
white adipose tissue
endothelial cells
adenosine
CD73
purinergic signaling
intercellular crosstalk
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1308456/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1308456/full

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