Frailty in Acute and Chronic Coronary Syndrome Patients Entering Cardiac Rehabilitation

Worldwide population ageing is partly due to advanced standard of care, leading to increased incidence and prevalence of geriatric syndromes such as frailty and disability. Hence, the age at the onset of acute coronary syndromes (ACS) keeps growing as well. Moreover, ageing is a risk factor for both...

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Main Authors: Francesco Giallauria, Anna Di Lorenzo, Elio Venturini, Mario Pacileo, Antonello D’Andrea, Umberto Garofalo, Felice De Lucia, Crescenzo Testa, Gianluigi Cuomo, Gabriella Iannuzzo, Marco Gentile, Cinzia Nugara, Filippo M Sarullo, Nastasia Marinus, Dominique Hansen, Carlo Vigorito
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/10/8/1696
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author Francesco Giallauria
Anna Di Lorenzo
Elio Venturini
Mario Pacileo
Antonello D’Andrea
Umberto Garofalo
Felice De Lucia
Crescenzo Testa
Gianluigi Cuomo
Gabriella Iannuzzo
Marco Gentile
Cinzia Nugara
Filippo M Sarullo
Nastasia Marinus
Dominique Hansen
Carlo Vigorito
author_facet Francesco Giallauria
Anna Di Lorenzo
Elio Venturini
Mario Pacileo
Antonello D’Andrea
Umberto Garofalo
Felice De Lucia
Crescenzo Testa
Gianluigi Cuomo
Gabriella Iannuzzo
Marco Gentile
Cinzia Nugara
Filippo M Sarullo
Nastasia Marinus
Dominique Hansen
Carlo Vigorito
author_sort Francesco Giallauria
collection DOAJ
description Worldwide population ageing is partly due to advanced standard of care, leading to increased incidence and prevalence of geriatric syndromes such as frailty and disability. Hence, the age at the onset of acute coronary syndromes (ACS) keeps growing as well. Moreover, ageing is a risk factor for both frailty and cardiovascular disease (CVD). Frailty and CVD in the elderly share pathophysiological mechanisms and associated conditions, such as malnutrition, sarcopenia, anemia, polypharmacy and both increased bleeding/thrombotic risk, leading to a negative impact on outcomes. In geriatric populations ACS is associated with an increased frailty degree that has a negative effect on re-hospitalization and mortality outcomes. Frail elderly patients are increasingly referred to cardiac rehabilitation (CR) programs after ACS; however, plans of care must be tailored on individual’s clinical complexity in terms of functional capacity, nutritional status and comorbidities, cognitive status, socio-economic support. Completing rehabilitative intervention with a reduced frailty degree, disability prevention, improvement in functional state and quality of life and reduction of re-hospitalization are the goals of CR program. Tools for detecting frailty and guidelines for management of frail elderly patients post-ACS are still debated. This review focused on the need of an early identification of frail patients in elderly with ACS and at elaborating personalized plans of care and secondary prevention in CR setting.
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spelling doaj.art-a3c345e0575e42468e15d0af430923132023-12-03T13:03:10ZengMDPI AGJournal of Clinical Medicine2077-03832021-04-01108169610.3390/jcm10081696Frailty in Acute and Chronic Coronary Syndrome Patients Entering Cardiac RehabilitationFrancesco Giallauria0Anna Di Lorenzo1Elio Venturini2Mario Pacileo3Antonello D’Andrea4Umberto Garofalo5Felice De Lucia6Crescenzo Testa7Gianluigi Cuomo8Gabriella Iannuzzo9Marco Gentile10Cinzia Nugara11Filippo M Sarullo12Nastasia Marinus13Dominique Hansen14Carlo Vigorito15Department of Translational Medical Sciences, “Federico II” University of Naples, 80131 Naples, ItalyDepartment of Translational Medical Sciences, “Federico II” University of Naples, 80131 Naples, ItalyCardiac Rehabilitation Unit, Azienda USL Toscana Nord-Ovest, Cecina Civil Hospital, 57023 Cecina (LI), ItalyDivision of Cardiology/UTIC, “Umberto I” Hospital, Nocera Inferiore (ASL Salerno), 84014 Nocera Inferiore (SA), ItalyDivision of Cardiology/UTIC, “Umberto I” Hospital, Nocera Inferiore (ASL Salerno), 84014 Nocera Inferiore (SA), ItalyDepartment of Translational Medical Sciences, “Federico II” University of Naples, 80131 Naples, ItalyDepartment of Translational Medical Sciences, “Federico II” University of Naples, 80131 Naples, ItalyDepartment of Translational Medical Sciences, “Federico II” University of Naples, 80131 Naples, ItalyDepartment of Translational Medical Sciences, “Federico II” University of Naples, 80131 Naples, ItalyDepartment of Clinical Medicine and Surgery, “Federico II” University of Naples, 80131 Naples, ItalyDepartment of Clinical Medicine and Surgery, “Federico II” University of Naples, 80131 Naples, ItalyCardiovascular Rehabilitation Unit, Buccheri La Ferla Fatebenefratelli Hospital, 90123 Palermo, ItalyCardiovascular Rehabilitation Unit, Buccheri La Ferla Fatebenefratelli Hospital, 90123 Palermo, ItalyREVAL-Rehabilitation Research Center, Faculty of Rehabilitation Sciences, Hasselt University, BE3590 Diepenbeek, BelgiumREVAL-Rehabilitation Research Center, Faculty of Rehabilitation Sciences, Hasselt University, BE3590 Diepenbeek, BelgiumDepartment of Translational Medical Sciences, “Federico II” University of Naples, 80131 Naples, ItalyWorldwide population ageing is partly due to advanced standard of care, leading to increased incidence and prevalence of geriatric syndromes such as frailty and disability. Hence, the age at the onset of acute coronary syndromes (ACS) keeps growing as well. Moreover, ageing is a risk factor for both frailty and cardiovascular disease (CVD). Frailty and CVD in the elderly share pathophysiological mechanisms and associated conditions, such as malnutrition, sarcopenia, anemia, polypharmacy and both increased bleeding/thrombotic risk, leading to a negative impact on outcomes. In geriatric populations ACS is associated with an increased frailty degree that has a negative effect on re-hospitalization and mortality outcomes. Frail elderly patients are increasingly referred to cardiac rehabilitation (CR) programs after ACS; however, plans of care must be tailored on individual’s clinical complexity in terms of functional capacity, nutritional status and comorbidities, cognitive status, socio-economic support. Completing rehabilitative intervention with a reduced frailty degree, disability prevention, improvement in functional state and quality of life and reduction of re-hospitalization are the goals of CR program. Tools for detecting frailty and guidelines for management of frail elderly patients post-ACS are still debated. This review focused on the need of an early identification of frail patients in elderly with ACS and at elaborating personalized plans of care and secondary prevention in CR setting.https://www.mdpi.com/2077-0383/10/8/1696frailtycardiovascular diseasecardiac rehabilitationacute coronary syndromechronic coronary syndromeexercise training
spellingShingle Francesco Giallauria
Anna Di Lorenzo
Elio Venturini
Mario Pacileo
Antonello D’Andrea
Umberto Garofalo
Felice De Lucia
Crescenzo Testa
Gianluigi Cuomo
Gabriella Iannuzzo
Marco Gentile
Cinzia Nugara
Filippo M Sarullo
Nastasia Marinus
Dominique Hansen
Carlo Vigorito
Frailty in Acute and Chronic Coronary Syndrome Patients Entering Cardiac Rehabilitation
Journal of Clinical Medicine
frailty
cardiovascular disease
cardiac rehabilitation
acute coronary syndrome
chronic coronary syndrome
exercise training
title Frailty in Acute and Chronic Coronary Syndrome Patients Entering Cardiac Rehabilitation
title_full Frailty in Acute and Chronic Coronary Syndrome Patients Entering Cardiac Rehabilitation
title_fullStr Frailty in Acute and Chronic Coronary Syndrome Patients Entering Cardiac Rehabilitation
title_full_unstemmed Frailty in Acute and Chronic Coronary Syndrome Patients Entering Cardiac Rehabilitation
title_short Frailty in Acute and Chronic Coronary Syndrome Patients Entering Cardiac Rehabilitation
title_sort frailty in acute and chronic coronary syndrome patients entering cardiac rehabilitation
topic frailty
cardiovascular disease
cardiac rehabilitation
acute coronary syndrome
chronic coronary syndrome
exercise training
url https://www.mdpi.com/2077-0383/10/8/1696
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