Imaging in Patients with Bisphosphonate-Associated Osteonecrosis of the Jaws (MRONJ)

Background: Bisphosphonate-associated osteonecrosis of the jaws (MRONJ/BP-ONJ/BRONJ) is a commonly seen disease. During recent decades, major advances in diagnostics have occurred. Once the clinical picture shows typical MRONJ features, imaging is necessary to determine the size of the lesion. Expos...

Full description

Bibliographic Details
Main Authors: Britt-Isabelle Berg, Andreas A. Mueller, Marcello Augello, Scott Berg, Claude Jaquiéry
Format: Article
Language:English
Published: MDPI AG 2016-09-01
Series:Dentistry Journal
Subjects:
Online Access:http://www.mdpi.com/2304-6767/4/3/29
_version_ 1798005776613113856
author Britt-Isabelle Berg
Andreas A. Mueller
Marcello Augello
Scott Berg
Claude Jaquiéry
author_facet Britt-Isabelle Berg
Andreas A. Mueller
Marcello Augello
Scott Berg
Claude Jaquiéry
author_sort Britt-Isabelle Berg
collection DOAJ
description Background: Bisphosphonate-associated osteonecrosis of the jaws (MRONJ/BP-ONJ/BRONJ) is a commonly seen disease. During recent decades, major advances in diagnostics have occurred. Once the clinical picture shows typical MRONJ features, imaging is necessary to determine the size of the lesion. Exposed bone is not always painful, therefore a thorough clinical examination and radiological imaging are essential when MRONJ is suspected. Methods: In this paper we will present the latest clinical update on the imaging options in regard to MRONJ: X-ray/Panoramic Radiograph, Cone Beam Computed Tomography (CBCT) and Computed Tomography (CT), Magnetic Resonance Imaging (MRI), Nuclear Imaging, Fluorescence-Guided Bone Resection. Conclusion: Which image modality is chosen depends not only on the surgeon’s/practitioner’s preference but also on the available imaging modalities. A three-dimensional imaging modality is desirable, and in severe cases necessary, for extended resections and planning of reconstruction.
first_indexed 2024-04-11T12:45:18Z
format Article
id doaj.art-a3c8fa3cbca549218310dc8730d6a1b8
institution Directory Open Access Journal
issn 2304-6767
language English
last_indexed 2024-04-11T12:45:18Z
publishDate 2016-09-01
publisher MDPI AG
record_format Article
series Dentistry Journal
spelling doaj.art-a3c8fa3cbca549218310dc8730d6a1b82022-12-22T04:23:23ZengMDPI AGDentistry Journal2304-67672016-09-01432910.3390/dj4030029dj4030029Imaging in Patients with Bisphosphonate-Associated Osteonecrosis of the Jaws (MRONJ)Britt-Isabelle Berg0Andreas A. Mueller1Marcello Augello2Scott Berg3Claude Jaquiéry4Department of Cranio-Maxillofacial Surgery, University Hospital Basel, 4056 Basel, SwitzerlandDepartment of Cranio-Maxillofacial Surgery, University Hospital Basel, 4056 Basel, SwitzerlandClinic of Cranio-Maxillofacial Surgery, Kantonsspital Aarau, 5001 Aarau, SwitzerlandPrivate Practice, 25524 Itzehoe, GermanyDepartment of Cranio-Maxillofacial Surgery, University Hospital Basel, 4056 Basel, SwitzerlandBackground: Bisphosphonate-associated osteonecrosis of the jaws (MRONJ/BP-ONJ/BRONJ) is a commonly seen disease. During recent decades, major advances in diagnostics have occurred. Once the clinical picture shows typical MRONJ features, imaging is necessary to determine the size of the lesion. Exposed bone is not always painful, therefore a thorough clinical examination and radiological imaging are essential when MRONJ is suspected. Methods: In this paper we will present the latest clinical update on the imaging options in regard to MRONJ: X-ray/Panoramic Radiograph, Cone Beam Computed Tomography (CBCT) and Computed Tomography (CT), Magnetic Resonance Imaging (MRI), Nuclear Imaging, Fluorescence-Guided Bone Resection. Conclusion: Which image modality is chosen depends not only on the surgeon’s/practitioner’s preference but also on the available imaging modalities. A three-dimensional imaging modality is desirable, and in severe cases necessary, for extended resections and planning of reconstruction.http://www.mdpi.com/2304-6767/4/3/29bisphosphonate-associated osteonecrosismagnetic resonance imagingpanoramic radiographcomputed tomographycone beam computed tomographysingle photon emission computed tomographypositron emission tomographyfluorescence-guided bone resection
spellingShingle Britt-Isabelle Berg
Andreas A. Mueller
Marcello Augello
Scott Berg
Claude Jaquiéry
Imaging in Patients with Bisphosphonate-Associated Osteonecrosis of the Jaws (MRONJ)
Dentistry Journal
bisphosphonate-associated osteonecrosis
magnetic resonance imaging
panoramic radiograph
computed tomography
cone beam computed tomography
single photon emission computed tomography
positron emission tomography
fluorescence-guided bone resection
title Imaging in Patients with Bisphosphonate-Associated Osteonecrosis of the Jaws (MRONJ)
title_full Imaging in Patients with Bisphosphonate-Associated Osteonecrosis of the Jaws (MRONJ)
title_fullStr Imaging in Patients with Bisphosphonate-Associated Osteonecrosis of the Jaws (MRONJ)
title_full_unstemmed Imaging in Patients with Bisphosphonate-Associated Osteonecrosis of the Jaws (MRONJ)
title_short Imaging in Patients with Bisphosphonate-Associated Osteonecrosis of the Jaws (MRONJ)
title_sort imaging in patients with bisphosphonate associated osteonecrosis of the jaws mronj
topic bisphosphonate-associated osteonecrosis
magnetic resonance imaging
panoramic radiograph
computed tomography
cone beam computed tomography
single photon emission computed tomography
positron emission tomography
fluorescence-guided bone resection
url http://www.mdpi.com/2304-6767/4/3/29
work_keys_str_mv AT brittisabelleberg imaginginpatientswithbisphosphonateassociatedosteonecrosisofthejawsmronj
AT andreasamueller imaginginpatientswithbisphosphonateassociatedosteonecrosisofthejawsmronj
AT marcelloaugello imaginginpatientswithbisphosphonateassociatedosteonecrosisofthejawsmronj
AT scottberg imaginginpatientswithbisphosphonateassociatedosteonecrosisofthejawsmronj
AT claudejaquiery imaginginpatientswithbisphosphonateassociatedosteonecrosisofthejawsmronj