Hemolysis in a Patient during Hemodialysis

We report a case of hemolysis during a hemodialysis (HD) session in a 71-year-old man. His end-stage kidney disease is secondary to light-chain amyloidosis with renal involvement. Despite immunosuppressive treatment, his renal function continued to decline, and dialysis had to be initiated. Peritone...

Full description

Bibliographic Details
Main Authors: Maxime Taghavi, Lucas Jacobs, Saleh Kaysi, Maria do Carmo Filomena Mesquita
Format: Article
Language:English
Published: Karger Publishers 2021-11-01
Series:Case Reports in Nephrology and Dialysis
Subjects:
Online Access:https://www.karger.com/Article/FullText/520559
_version_ 1818971174054395904
author Maxime Taghavi
Lucas Jacobs
Saleh Kaysi
Maria do Carmo Filomena Mesquita
author_facet Maxime Taghavi
Lucas Jacobs
Saleh Kaysi
Maria do Carmo Filomena Mesquita
author_sort Maxime Taghavi
collection DOAJ
description We report a case of hemolysis during a hemodialysis (HD) session in a 71-year-old man. His end-stage kidney disease is secondary to light-chain amyloidosis with renal involvement. Despite immunosuppressive treatment, his renal function continued to decline, and dialysis had to be initiated. Peritoneal dialysis (PD) was started but that had to be converted to HD because of pleural effusion due to PD fluid leakage. On the event day, the patient presented a respiratory distress 2 h after the initiation of HD. He developed a sudden onset of dyspnea with hypoxemia, associated with abdominal pain, nausea, and vomiting. He also presented chest pain with arterial hypertension. The pre-pump arterial and post-pump pressures were, respectively, 40 and 100 mm Hg, with no machine alarm. The blood color in the circuit changed and became darker, so HD was stopped immediately without blood restitution, and then a blood workup was obtained, and the patient was treated with oxygen therapy, IV methylprednisolone 40 mg, and IV furosemide 100 mg. Tubing checkup performed after the incident showed a kinked arterial tube which led to the suspicion of acute hemolysis. Blood transfusion was therefore urgently ordered, and the patient was immediately transferred to the intensive care unit (ICU). Artificial ventilation was required for 4 days, with initial massive blood transfusion. A 24-h treatment with extracorporeal cytokine adsorber CytoSorb® was also performed, followed by the regular HD sessions thrice weekly. Evolution was favorable, and the patient was discharged from the ICU 18 days later.
first_indexed 2024-12-20T14:48:10Z
format Article
id doaj.art-a3cbbb31ba7e46b8912344dd75c29fbb
institution Directory Open Access Journal
issn 2296-9705
language English
last_indexed 2024-12-20T14:48:10Z
publishDate 2021-11-01
publisher Karger Publishers
record_format Article
series Case Reports in Nephrology and Dialysis
spelling doaj.art-a3cbbb31ba7e46b8912344dd75c29fbb2022-12-21T19:37:04ZengKarger PublishersCase Reports in Nephrology and Dialysis2296-97052021-11-0111334835410.1159/000520559520559Hemolysis in a Patient during HemodialysisMaxime TaghaviLucas Jacobshttps://orcid.org/0000-0001-8148-0349Saleh KaysiMaria do Carmo Filomena MesquitaWe report a case of hemolysis during a hemodialysis (HD) session in a 71-year-old man. His end-stage kidney disease is secondary to light-chain amyloidosis with renal involvement. Despite immunosuppressive treatment, his renal function continued to decline, and dialysis had to be initiated. Peritoneal dialysis (PD) was started but that had to be converted to HD because of pleural effusion due to PD fluid leakage. On the event day, the patient presented a respiratory distress 2 h after the initiation of HD. He developed a sudden onset of dyspnea with hypoxemia, associated with abdominal pain, nausea, and vomiting. He also presented chest pain with arterial hypertension. The pre-pump arterial and post-pump pressures were, respectively, 40 and 100 mm Hg, with no machine alarm. The blood color in the circuit changed and became darker, so HD was stopped immediately without blood restitution, and then a blood workup was obtained, and the patient was treated with oxygen therapy, IV methylprednisolone 40 mg, and IV furosemide 100 mg. Tubing checkup performed after the incident showed a kinked arterial tube which led to the suspicion of acute hemolysis. Blood transfusion was therefore urgently ordered, and the patient was immediately transferred to the intensive care unit (ICU). Artificial ventilation was required for 4 days, with initial massive blood transfusion. A 24-h treatment with extracorporeal cytokine adsorber CytoSorb® was also performed, followed by the regular HD sessions thrice weekly. Evolution was favorable, and the patient was discharged from the ICU 18 days later.https://www.karger.com/Article/FullText/520559hemolysishemodialysisfaulty blood tubing setskinking of bloodlines
spellingShingle Maxime Taghavi
Lucas Jacobs
Saleh Kaysi
Maria do Carmo Filomena Mesquita
Hemolysis in a Patient during Hemodialysis
Case Reports in Nephrology and Dialysis
hemolysis
hemodialysis
faulty blood tubing sets
kinking of bloodlines
title Hemolysis in a Patient during Hemodialysis
title_full Hemolysis in a Patient during Hemodialysis
title_fullStr Hemolysis in a Patient during Hemodialysis
title_full_unstemmed Hemolysis in a Patient during Hemodialysis
title_short Hemolysis in a Patient during Hemodialysis
title_sort hemolysis in a patient during hemodialysis
topic hemolysis
hemodialysis
faulty blood tubing sets
kinking of bloodlines
url https://www.karger.com/Article/FullText/520559
work_keys_str_mv AT maximetaghavi hemolysisinapatientduringhemodialysis
AT lucasjacobs hemolysisinapatientduringhemodialysis
AT salehkaysi hemolysisinapatientduringhemodialysis
AT mariadocarmofilomenamesquita hemolysisinapatientduringhemodialysis