Stress-Driven Discovery of Novel Cryptic Antibiotics from a Marine Fungus Penicillium sp. BB1122

Stress-Driven Discovery of Novel Cryptic Antibiotics from a Marine Fungus Penicillium sp. BB1122

Standard laboratory cultures have long been known to hinder activation of specific gene clusters which in turn hamper production of secondary metabolites with unique properties due to lack of innovation or the inability to trigger cryptic gene clusters’ expression. Due to challenges related to the a...

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Bibliographic Details
Main Authors: Bibi N. Auckloo, Chengqian Pan, Najeeb Akhter, Bin Wu, Xiaodan Wu, Shan He
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Microbiology
Subjects:
marine fungus
metal-stress strategy
spectroscopic techniques
polyketide
antibiotics
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2017.01450/full

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