Interfering with TGFβ-induced Smad3 nuclear accumulation differentially affects TGFβ-dependent gene expression

Interfering with TGFβ-induced Smad3 nuclear accumulation differentially affects TGFβ-dependent gene expression

<p>Abstract</p> <p>Background</p> <p>Transforming growth factor-β (TGFβ) plays an important role in late-stage carcinogenesis by stimulating invasive behavior of cancer cells, promoting neo-angiogenesis and by helping cancer cells to escape surveillance by the immune sy...

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Bibliographic Details
Main Authors: Dittmer Jürgen, Nordheim Alfred, Lindemann Ralph K
Format: Article
Language:English
Published: BMC 2003-03-01
Series:Molecular Cancer
Subjects:
breast tumor
invasiveness
Ets factors
PTHrP
Smad3
Online Access:http://www.molecular-cancer.com/content/2/1/20

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